Benzoimidazole-6-nitro

Base Information

• Chemical Name: Benzoimidazole-6-nitro
• CAS No.: 89843-47-0
• Molecular Formula: C₇H₅N₃O₂
• Molecular Weight: 163.136
• Mol file: 89843-47-0.mol

Synonyms:BENZOIMIDAZOLE-6-NITRO;Benzimidazole, 5-nitro-;5-Nitro-1H-benzimidazole;1H-Benzimidazole, 5-nitro-;5(6)-Nitrobenzimidazole;Benzimidazole, 5(or 6)-nitro-;

Chemical Property of Benzoimidazole-6-nitro

Chemical Property:

• PSA: 74.50000
• LogP: 1.99430

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoimidazole-6-nitro

There total 16 articles about Benzoimidazole-6-nitro which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

→ 6-nitro-1H-benzo[d]imidazole (94-52-0,89843-47-0)

Guidance literature:

at 120 ℃; for 1h; Microwave irradiation;

Reference yield: 94.0%

formic acid (64-18-6) + 4-Nitrophenylene-1,2-diamine (99-56-9) → 6-nitro-1H-benzo[d]imidazole (94-52-0,89843-47-0)

Guidance literature:

With Na⁺-MMT-[pmim]HSO₄; In neat (no solvent); at 60 ℃; for 0.25h; chemoselective reaction;

DOI:10.1007/s11164-015-2116-0

Reference yield: 91.0%

orthoformic acid triethyl ester (122-51-0) + 4-Nitrophenylene-1,2-diamine (99-56-9) → 6-nitro-1H-benzo[d]imidazole (94-52-0,89843-47-0)

Guidance literature:

With sulfonated rice husk ash; In neat (no solvent); at 80 ℃; for 0.0666667h;

DOI:10.1007/s11164-014-1685-7

upstream raw materials:

benzoimidazole

2,4-Dinitro-formanilid

2,4-Dinitroanilin

orthoformic acid triethyl ester

Downstream raw materials:

(E)-1-(6-nitro-1H-benzo[d]imidazol-1-yl)-3-phenylprop-2-en-1-one

Refernces

• 1、 -. "ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE "RIG-I' PATHWAY AND METHODS OF USE THEREOF". . . Retrieved 2020/03/05.
• 2、 Deng, Guobo,Kuang, Daizhi,Liang, Yun,Yang, Yuan,Yu, Jiangxi,Zhang, Fuxing,Zhu, Xiaoming. "K2S as Sulfur Source and DMSO as Carbon Source for the Synthesis of 2-Unsubstituted Benzothiazoles". supporting information. p. 3789 - 3793. Retrieved 2020/06/04.