4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenol

Base Information

Chemical Name:4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenol
CAS No.:898563-26-3
Molecular Formula:C15H13N3O
Molecular Weight:251.288
Hs Code.:
Mol file:898563-26-3.mol

Synonyms:4-(1-Methyl-4-pyridin-4-yl-1H -pyrazol-3-yl)-phenol;4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenol;4-(1-methyl-4-pyridin-4-yl-pyrazol-3-yl)-phenol;

Suppliers and Price of 4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenol

Chemical Property:

PSA：50.94000
LogP:2.85470

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenol

There total 6 articles about 4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 898563-25-2
4-[3-(4-benzyloxy-phenyl)-1-methyl-1H-pyrazol-4-yl]-pyridine

: 898563-26-3
4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenol

Guidance literature:: With hydrogen; palladium dihydroxide; In ethanol; ethyl acetate; for 6h; under 2068.65 Torr;

Reference yield:

: 252199-28-3
4-(benzyloxy)-N-methoxy-N-methylbenzamide

: 898563-26-3
4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenol

Guidance literature:: Multi-step reaction with 2 steps

1: lithium diisopropyl amide / -78 - 20 °C

2: Reflux

With lithium diisopropyl amide;
DOI:10.1039/c2md20239e

Reference yield:

: 1486-51-7
p-(benzyloxy)benzoic acid

: 898563-26-3
4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenol

Guidance literature:: Multi-step reaction with 3 steps

1: 1,1'-carbonyldiimidazole; triethylamine / dichloromethane / 20 °C

2: lithium diisopropyl amide / -78 - 20 °C

3: Reflux

With triethylamine; 1,1'-carbonyldiimidazole; lithium diisopropyl amide; In dichloromethane;
DOI:10.1039/c2md20239e