4,5-Bis(bromomethyl)-2-phenyl-1,3-oxazole

Base Information

Chemical Name:4,5-Bis(bromomethyl)-2-phenyl-1,3-oxazole
CAS No.:90127-53-0
Molecular Formula:C11H9Br2NO
Molecular Weight:331.007
Hs Code.:
DSSTox Substance ID:DTXSID30529693
Wikidata:Q82400301

Synonyms:4,5-Bis(bromomethyl)-2-phenyl-1,3-oxazole;90127-53-0;DTXSID30529693;2-phenyl-4,5-bis(bromomethyl)oxazole

Suppliers and Price of 4,5-Bis(bromomethyl)-2-phenyl-1,3-oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4,5-Bis(bromomethyl)-2-phenyl-1,3-oxazole

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:330.90304
Heavy Atom Count:15
Complexity:197

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC(=C(O2)CBr)CBr

Technology Process of 4,5-Bis(bromomethyl)-2-phenyl-1,3-oxazole

There total 3 articles about 4,5-Bis(bromomethyl)-2-phenyl-1,3-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 26028-53-5
4,5-dimethyl-2-phenyl-oxazole

: 90127-53-0
2-phenyl-4,5-bis(bromomethyl)oxazole

Guidance literature:: With N-Bromosuccinimide; In tetrachloromethane; at 20 ℃; for 1h;
DOI:10.1016/j.molstruc.2016.02.033

Reference yield:

: 55-21-0,27208-38-4
benzamide

: 90127-53-0
2-phenyl-4,5-bis(bromomethyl)oxazole

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 18 h / 120 °C / Inert atmosphere

2: N-Bromosuccinimide / tetrachloromethane / 1 h / 20 °C

With N-Bromosuccinimide; acetic acid; In tetrachloromethane;
DOI:10.1016/j.molstruc.2016.02.033

Reference yield:

: 18227-62-8
(+/-)-2-benzamido-3-butanone

: 90127-53-0
2-phenyl-4,5-bis(bromomethyl)oxazole

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / H₂SO₄ (conc.), Ac₂O / 1 h / Heating

2: 89 percent / NBS / CCl₄ / 1 h / Heating

With N-Bromosuccinimide; sulfuric acid; acetic anhydride; In tetrachloromethane;
DOI:10.1007/BF00956242