2-[(Isoquinolin-4-yl)methyl]phenol

Base Information

Chemical Name:2-[(Isoquinolin-4-yl)methyl]phenol
CAS No.:90136-93-9
Molecular Formula:C₁₆H₁₃NO
Molecular Weight:235.285
Hs Code.:
DSSTox Substance ID:DTXSID40521704

Synonyms:2-[(Isoquinolin-4-yl)methyl]phenol;90136-93-9;4-(2-hydroxybenzyl)isoquinoline;DTXSID40521704

Suppliers and Price of 2-[(Isoquinolin-4-yl)methyl]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-[(Isoquinolin-4-yl)methyl]phenol

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:235.099714038
Heavy Atom Count:18
Complexity:268

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=NC=C2CC3=CC=CC=C3O

Technology Process of 2-[(Isoquinolin-4-yl)methyl]phenol

There total 1 articles about 2-[(Isoquinolin-4-yl)methyl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 3230-65-7
3,4-dihydroisoquinoline

: 90-01-7
salicylic alcohol

: 90136-93-9
4-(o-hydroxybenzyl)-isoquinoline

Guidance literature:: at 170 ℃; for 8h;
DOI:10.1016/0040-4020(84)85123-6

Reference yield: 67.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 90136-93-9
4-(o-hydroxybenzyl)-isoquinoline

: 90136-94-0
4-(o-methoxybenzyl)-isoquinoline

Guidance literature:: In methanol;
DOI:10.1016/0040-4020(84)85123-6

Reference yield:

: 90136-93-9
4-(o-hydroxybenzyl)-isoquinoline

: 90136-96-2
N-methyl-4-(o-methoxybenzyl)-1.2.3.4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / methanol

2: 2.) NaBH₄ / 1.) reflux, 15 h; 2.) 90percent ethanol

With sodium tetrahydroborate; In methanol;
DOI:10.1016/0040-4020(84)85123-6