4-[(2-Methoxyphenyl)methyl]isoquinoline

Base Information

Chemical Name:4-[(2-Methoxyphenyl)methyl]isoquinoline
CAS No.:90136-94-0
Molecular Formula:C₁₇H₁₅NO
Molecular Weight:249.312
Hs Code.:
DSSTox Substance ID:DTXSID60521706
Wikidata:Q82386335

Synonyms:90136-94-0;4-(2-Methoxybenzyl)isoquinoline;4-[(2-Methoxyphenyl)methyl]isoquinoline;DTXSID60521706

Suppliers and Price of 4-[(2-Methoxyphenyl)methyl]isoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-[(2-Methoxyphenyl)methyl]isoquinoline

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:249.115364102
Heavy Atom Count:19
Complexity:280

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1CC2=CN=CC3=CC=CC=C32

Technology Process of 4-[(2-Methoxyphenyl)methyl]isoquinoline

There total 4 articles about 4-[(2-Methoxyphenyl)methyl]isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 90136-93-9
4-(o-hydroxybenzyl)-isoquinoline

: 90136-94-0
4-(o-methoxybenzyl)-isoquinoline

Guidance literature:: In methanol;
DOI:10.1016/0040-4020(84)85123-6

Reference yield: 16.0%

: 91-21-4
1,2,3,4-tetrahydroisoquinoline

: 135-02-4
ortho-anisaldehyde

: 90136-94-0
4-(o-methoxybenzyl)-isoquinoline

Guidance literature:: With acetic acid; In toluene; for 48h; Heating;
DOI:10.1002/ardp.19863191105

Reference yield:

: 3230-65-7
3,4-dihydroisoquinoline

: 90136-94-0
4-(o-methoxybenzyl)-isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 55 percent / 8 h / 170 °C

2: 67 percent / methanol

In methanol;
DOI:10.1016/0040-4020(84)85123-6