N-Methyl-N-phenylcarbodiimide

Base Information

• Chemical Name: N-Methyl-N-phenylcarbodiimide
• CAS No.: 4172-91-2
• Molecular Formula: C8H8N2
• Molecular Weight: 132.165
• Hs Code.: 2925290090
• Mol file: 4172-91-2.mol

Synonyms:Ph-N=C=N-CH3;N-Methyl-N'-phenylcarbodiimide;N-((methylimino)methylene)aniline;N'-methyl-N-phenylmethanediimine;methyl(phenyl)carbodiimide;

Chemical Property of N-Methyl-N-phenylcarbodiimide

Chemical Property:

• Boiling Point: 209°Cat760mmHg
• Flash Point: 71.7°C
• PSA: 24.72000
• Density: 0.93g/cm³
• LogP: 2.12180

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Methyl-N-phenylcarbodiimide

There total 31 articles about N-Methyl-N-phenylcarbodiimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-methyl-3-phenylthiourea (2724-69-8) → N-((methylimino)methylene)aniline (4172-91-2)

Guidance literature:

With dmap; methanesulfonyl chloride; triethylamine; In dichloromethane; for 0.0833333h; Ambient temperature;

DOI:10.1080/00397919508010787

Reference yield: 90.0%

1-methyl-3-phenylurea (1007-36-9) → N-((methylimino)methylene)aniline (4172-91-2)

Guidance literature:

With triphenylphosphine dibromide 1:1 addition complex; triethylamine; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1055/s-1981-29454

Reference yield: 89.0%

4-methyl-5-phenylimino-Δ2-1,2,3,4-thiatriazoline (34551-29-6) → N-((methylimino)methylene)aniline (4172-91-2)

Guidance literature:

In [D₃]acetonitrile; at 20 ℃; for 10h; Irradiation;

upstream raw materials:

heptamethyldisilazane

phenylcarbonimidic dichloride

dimethylaluminium-(N-methyl-trimethylsilyl)amide

phenyl isocyanate

Downstream raw materials:

1-Methyl-3-phenyl-4-[(Z)-phenylimino]-[1,3]diazetidin-2-one

3-methyl-2,4-bis(phenylimino)-1,3-thiazetidine

C₁₁H₁₂N₂O

(4-(4-methoxyphenyl)-1,6-dimethyl-1,3,5-triazin-2-ylidene)phenylamine

Refernces

• 1、 Ruiz, Javier,Sol, Daniel,Mateo, María A.,Vivanco, Marilín. "Selective formation of formamidines, carbodiimides and formimidates from isocyanide complexes of Mn(i) mediated by Ag2O". supporting information. p. 6279 - 6282. Retrieved 2018/05/23.
• 2、 Begue, Didier,Qiao, Greg Guanghua,Wentrup, Curt. "Nitrile imines: Matrix isolation, IR spectra, structures, and rearrangement to carbodiimides". scheme or table. p. 5339 - 5350. Retrieved 2012/05/20.