1007-36-9

Basic information

• Product Name: 1-METHYL-3-PHENYLUREA
• Synonyms: TIMTEC-BB SBB008334;1-methyl-3-phenyl-ure;Defenuron;n-methyl-n’-phenylurea;N-methyl-N’-phenyl-urea;N-Methyl-N'-phenylurea;N-Phenyl-N'-methylurea;Urea, 1-methyl-3-phenyl-
• CAS NO: 1007-36-9
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.18
• Mol File: 1007-36-9.mol
• Article Data: 25

Chemical Properties

• Melting Point: 154-155℃
• Boiling Point: 271.72°C (rough estimate)
• Flash Point: 98.9°C
• Appearance: /
• Density: 1.1392 (rough estimate)
• Vapor Pressure: 0.0592mmHg at 25°C
• Refractive Index: 1.6180 (estimate)
• PKA: 12.77±0.46(Predicted)
• Water Solubility: 740g/L(45 oC)
• CAS DataBase Reference: 1-METHYL-3-PHENYLUREA(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-3-PHENYLUREA(1007-36-9)
• EPA Substance Registry System: 1-METHYL-3-PHENYLUREA(1007-36-9)

Safety Data

• Hazardous Substances Data: 1007-36-9(Hazardous Substances Data)

Usage

General Description

1-Methyl-3-phenylurea is an organic chemical compound characterized by its aromatic phenyl ring structure attached to the urea group. The compound's unique molecular structure gives it the ability to form hydrogen bonds with other molecules, which can be pivotal in many biochemical processes. The molecular formula of 1-Methyl-3-phenylurea is C9H10N2O, and its properties include a molar mass of approximately 162.19 g/mol, with a high boiling point. Its solubility in water and other solvents depends on factors like temperature and pressure. This chemical is often used in academic and industrial chemistry research, but as with all chemicals, it should be handled with care, as it could cause harm if improperly used.

InChI:InChI=1/C8H10N2O/c1-9-8(11)10-7-5-3-2-4-6-7/h2-6H,1H3,(H2,9,10,11)

Upstream product

• 103-71-9 phenyl isocyanate 
• 74-89-5 methylamine 
• 26891-98-5 (Methylcarbamoyl)azid 
• 62-53-3 aniline 
• 598-50-5 N-Methylurea 
• 2724-69-8 1-methyl-3-phenylthiourea 
• 63105-07-7 3-methyl-4-phenyl-3H-[1,2,3,5]oxathiadiazole 2-oxide 
• 33026-77-6 N-(phenyl)-N'-phenylmethoxyurea 
• 40848-79-1 C₁₄H₁₁Cl₂NO 
• 32903-84-7 Hexamethylendi-(N-nitroso-N'-phenylharnstoff) 
• 20123-39-1 3-(N-methylcarbamoyl)-1,3-diphenyltriazene 
• 41890-17-9 N¹-Chlor-N²-methylbenzamidin 
• 87343-78-0 C₁₅H₁₃ClN₂O₃ 
• 87343-76-8 C₁₅H₁₃ClN₂O₃ 

Downstream Products

• 603-54-3 N,N-diphenylurea 
• 14577-03-8 1-(4-chlorophenyl)-4-phenylsemicarbazide 
• 736157-97-4 5-ethyl-1-methyl-3-phenyl-barbituric acid 
• 27503-89-5 5,5-diallyl-1-methyl-3-phenyl-pyrimidine-2,4,6-trione 
• 27503-88-4 5,5-diethyl-1-methyl-3-phenyl-barbituric acid 
• 5841-17-8 3-methyl-5-phenyl-2-phenylimino-oxazolidin-4-one 
• 5586-66-3 N_.N'-Dimethyl-N-(phenylcarbamoyl)-formamidin 
• 21561-99-9 N-methyl-N'-phenyl-N-nitrosourea 
• 37412-30-9 3,6-dimethyl-1-phenyluracil 
• 80820-83-3 3-Methyl-1-phenyl-5-(4-tolyl)biuret 
• 42212-19-1 6-amino-3-methyl-1-phenylpyrimidine-2,4(1H,3H)dione 
• 856352-27-7 N'-(2,4-dinitro-phenyl)-N-methyl-N-nitro-urea 
• 208538-96-9 [Pt(N(C₆H₅)CON(CH₃)C(S)S)(P(C₆H₅)3)2]*CHCl₃ 

Relevant articles and documents

Chloromethylated polystyrene immobilized ruthenium complex of 2-(2-pyridyl)benzimidazole catalyst for the synthesis of bioactive disubstituted ureas by carbonylation reaction

Polymer supported transition metal complex catalysts have numerous applications as heterogeneous catalysts due to their ease of synthesis and commercial availability. Ru-Py-Merf was synthesized by anchoring 2-(2-pyridyl)benzimidazole to the polymer matrix, followed by loading of ruthenium salt. This Ru-Py-Merf material was thoroughly characterized by FTIR spectroscopy, UV-vis absorption spectroscopy, FE-SEM analysis, EDAX analysis, CHN analysis, AAS spectroscopy and TGA. Ru-Py-Merf showed excellent catalytic activity in the synthesis of symmetric and asymmetric disubstituted ureas by reductive carbonylation of nitrobenzenes and anilines. The as-synthesized Ru-Py-Merf catalyst is entirely heterogeneous in nature, thermally stable and can be easily reused up to six times.

-

-

Splitting a Substrate into Three Parts: Gold-Catalyzed Nitrogenation of Alkynes by C-C and C≡C Bond Cleavage

A gold-catalyzed nitrogenation of alkynes for the synthesis of carbamides and amino tetrazoles through C-C and C≡C bond cleavages is described. A diverse set of functionalized carbamide and amino tetrazole derivatives were selectively constructed under mild conditions. The chemoselectivity can be easily switched by the selection of the acid additives. The reaction is characterized by its broad substrate scope, direct construction of high value products, easy operation under air, and mild conditions at room temperature. This chemistry provides a way to transform alkynes by splitting the substrate into three parts.

The vinyl moiety as a handle for regiocontrol in the preparation of unsymmetrical 2,3-aliphatic-substituted indoles and pyrroles

Rho-Rho-Rho your boat: A rhodium catalyst effects the regioselective oxidative coupling of enynes with N-aryl ureas (X=NR2) and N-vinylacetamides (X=C(O)Me), affording the corresponding 2-alkenylindoles and 2-alkenylpyrroles in good yield. Simple hydrogenation delivers the C2/C3-aliphatic-substituted indole or pyrrole (see scheme).