2-[[2-(Boc-amino)ethyl]amino]acetic acid

Base Information

Chemical Name:2-[[2-(Boc-amino)ethyl]amino]acetic acid
CAS No.:90495-99-1
Molecular Formula:C9H18N2O4
Molecular Weight:218.25000
Hs Code.:
DSSTox Substance ID:DTXSID00431471
Nikkaji Number:J817.508J
Wikidata:Q82245365
Mol file:90495-99-1.mol

Synonyms:2-[[2-(Boc-amino)ethyl]amino]acetic acid;90495-99-1;2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]acetic Acid;(N'-Boc-2'-aminoethyl)glycine;Glycine, N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-;MFCD11974252;2-[(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]acetic acid;2-[[2-(Boc-amino)ethyl]amino]aceticAcid;(N-Boc-2-aminoethyl)glycine;SCHEMBL2153073;[2-(Boc-Amino)ethyl]-Gly-OH;DTXSID00431471;(N'-Boc-2'-aminoethyl) glycine;LZQSLXNZORCPAR-UHFFFAOYSA-N;AC1035;AKOS027256645;CS-11924;SY033323;CS-0372602;FT-0770110;EN300-135497;N-alpha-(2-t-Butoxycarbonyl-aminoethyl)-glycine;A860789;N-(2-tert-butoxycarbonylaminoethyl)aminoacetic acid;2-((2-((tert-Butoxycarbonyl)amino)ethyl)amino)acetic acid

Suppliers and Price of 2-[[2-(Boc-amino)ethyl]amino]acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-[[2-(Boc-amino)ethyl]amino]aceticAcid
50mg
$ 65.00

Crysdot
2-[[2-(Boc-amino)ethyl]amino]aceticAcid 95+%
5g
$ 713.00

Chemenu
2-[[2-(Boc-amino)ethyl]amino]aceticAcid 95%
5g
$ 667.00

AK Scientific
2-[[2-(Boc-amino)ethyl]amino]aceticacid
1g
$ 417.00

AK Scientific
2-[[2-(Boc-amino)ethyl]amino]aceticacid
250mg
$ 195.00

Activate Scientific
2-[[2-(Boc-amino)ethyl]amino]acetic Acid 95+%
5 g
$ 1127.00

Activate Scientific
2-[[2-(Boc-amino)ethyl]amino]acetic Acid 95+%
250 mg
$ 191.00

Activate Scientific
2-[[2-(Boc-amino)ethyl]amino]acetic Acid 95+%
1 g
$ 379.00

Total 8 raw suppliers

Chemical Property of 2-[[2-(Boc-amino)ethyl]amino]acetic acid

Chemical Property:

PSA：91.15000
LogP:0.78060
XLogP3:-2.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:218.12665706
Heavy Atom Count:15
Complexity:223

Purity/Quality:

97% ^*data from raw suppliers

2-[[2-(Boc-amino)ethyl]amino]aceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCCNCC(=O)O

Technology Process of 2-[[2-(Boc-amino)ethyl]amino]acetic acid

There total 11 articles about 2-[[2-(Boc-amino)ethyl]amino]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.3%

: 174799-94-1
benzyl 2-(benzyl{2-[(tert-butoxycarbonyl)amino]ethyl}amino)acetate

: 90495-99-1
N-(2-tert-butoxycarbonylaminoethyl)aminoacetic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 4h; under 3102.9 Torr; Ambient temperature;
DOI:10.1021/jo961580e

Reference yield: 46.5%

: 57260-73-8
N-BOC-1,2-diaminoethane

: 298-12-4
Glyoxilic acid

: 90495-99-1
N-(2-tert-butoxycarbonylaminoethyl)aminoacetic acid

Guidance literature:: N-BOC-1,2-diaminoethane; Glyoxilic acid; In water; at 35 ℃;

With 5%-palladium/activated carbon; hydrogen; In water; for 24h;
DOI:10.1007/s00726-011-0884-4

Reference yield:

: 57260-73-8
N-BOC-1,2-diaminoethane

: 90495-99-1
N-(2-tert-butoxycarbonylaminoethyl)aminoacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: molecular sieves 3 Angstroem / methanol / 4 h / 20 °C

1.2: 61 percent / NaBH₄ / methanol / 16 h / -5 °C

2.1: 90 percent / DIEA / dimethylformamide / 0 - 20 °C

3.1: 70 percent / ammonium formate / Pd/C / methanol / 16 h / Heating

With 3 A molecular sieve; ammonium formate; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm050256l