5-Hydroxyplatyphyllone M

Base Information

Chemical Name:5-Hydroxyplatyphyllone M
CAS No.:41137-85-3
Molecular Formula:C19H22O4
Molecular Weight:314.381
Hs Code.:2914501900
European Community (EC) Number:826-202-6
DSSTox Substance ID:DTXSID90537754
Nikkaji Number:J16.428C
Wikidata:Q82412852
Mol file:41137-85-3.mol

Synonyms:hirsutanonol;5-Hydroxy-3-platyphyllone;7,7-diphenyl-4,5,6,6a-tetrahydro-1H,3H-pyrrolo<1,2-c>oxazol-2-one;

Suppliers and Price of 5-Hydroxyplatyphyllone M

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Platyphyllonol 95+%
5mg
$ 730.00

Arctom
Platyphyllonol ≥98%
5mg
$ 463.00

Total 14 raw suppliers

Chemical Property of 5-Hydroxyplatyphyllone M

Chemical Property:

Boiling Point:575.2±50.0 °C(Predicted)
PKA:9.97±0.15(Predicted)
PSA：77.76000
Density:1 +-.0.06 g/cm3(Predicted)
LogP:2.98330
XLogP3:2.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:314.15180918
Heavy Atom Count:23
Complexity:341

Purity/Quality:

98%min ^*data from raw suppliers

Platyphyllonol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CCC(CC(=O)CCC2=CC=C(C=C2)O)O)O

Technology Process of 5-Hydroxyplatyphyllone M

There total 22 articles about 5-Hydroxyplatyphyllone M which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 22608-12-4,24939-16-0,33171-05-0,91884-88-7
bisdemethoxycurcumin

: 41137-85-3,93604-01-4,57089-26-6,79120-39-1
(+/-)-5-hydroxy-1,7-bis-(4'-hydroxyphenyl)-3-heptanone

: 113482-94-3
1,7-bis(4-hydroxyphenyl)heptane-3,5-dione

Guidance literature:: With palladium on activated charcoal;
DOI:10.1007/s11418-011-0599-6

Reference yield:

: 5597-50-2
3-(4-hydroxyphenyl)propionic acid methyl ester

: 41137-85-3,93604-01-4,57089-26-6,79120-39-1
(+/-)-5-hydroxy-1,7-bis-(4'-hydroxyphenyl)-3-heptanone

Guidance literature:: Multi-step reaction with 5 steps

1.1: 93 percent / p-toluenesulfonic acid monohydrate / CH₂Cl₂ / 1.5 h / 20 °C

2.1: 97 percent / LiAlH₄ / diethyl ether / 1.5 h / 20 °C

3.1: 67 percent / pyridinium chlorochromate (PCC); sodium acetate / CH₂Cl₂ / 2 h

4.1: tetrahydrofuran / 0.5 h / -78 °C

4.2: 71 percent / tetrahydrofuran / 2 h / -78 °C

5.1: AcOH; H₂O / tetrahydrofuran

With lithium aluminium tetrahydride; water; sodium acetate; toluene-4-sulfonic acid; acetic acid; pyridinium chlorochromate; In tetrahydrofuran; diethyl ether; dichloromethane; 1.1: protection / 2.1: Reduction / 3.1: Oxidation / 4.1: Metallation / 4.2: Condensation / 5.1: deprotection;
DOI:10.1023/A:1020847423427