(1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one

Base Information

Chemical Name:(1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one
CAS No.:52328-96-8
Molecular Formula:C19H16O4
Molecular Weight:308.334
Hs Code.:
DSSTox Substance ID:DTXSID001014705
Nikkaji Number:J1.541.810I,J845.468J
Wikidata:Q76303632
Metabolomics Workbench ID:123294
ChEMBL ID:CHEMBL131770
Mol file:52328-96-8.mol

Synonyms:52328-96-8;CHEMBL131770;(1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one;1,4,6-Heptatrien-3-one, 5-hydroxy-1,7-bis(4-hydroxyphenyl)-,(1E,4Z,6E)-;(1E,4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one;p,p-hydroxy-curucumin;1,4,6-Heptatrien-3-one;MLS002473127;SCHEMBL609967;MEGxp0_001762;1,4,6-Heptatrien-3-one, 5-hydroxy-1,7-bis(4-hydroxyphenyl)-, (Z,E,E)-;ACon1_002080;DTXSID001014705;HMS2224E08;VUF-9014;BDBM50145907;AKOS040762832;NCGC00179852-01;SMR001397224;C17743;A930227;1,7-Bis(4-hydroxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one;(1E,4Z,6E)-1,7-Bis(4-hydroxyphenyl)-5-hydroxy-1,4,6-heptatriene-3-one;(Z,E,E)-5-Hydroxy-1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one;InChI=1/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-13,20-22H/b11-5+,12-6+,18-13

Suppliers and Price of (1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of (1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one

Chemical Property:

Boiling Point:553.4±50.0 °C(Predicted)
PKA:8.37±0.60(Predicted)
PSA：77.76000
Density:1.319±0.06 g/cm3(Predicted)
LogP:3.83540
XLogP3:4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:308.10485899
Heavy Atom Count:23
Complexity:462

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C=CC(=CC(=O)C=CC2=CC=C(C=C2)O)O)O
Isomeric SMILES:C1=CC(=CC=C1/C=C/C(=C/C(=O)/C=C/C2=CC=C(C=C2)O)/O)O

Technology Process of (1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one

There total 9 articles about (1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: C₃₈H₃₀CaO₈

: 52328-96-8
bis-demethoxycurcumin

Guidance literature:: In water; at 20 ℃; for 12h; pH=5; Large scale;

Reference yield: 88.0%

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 123-54-6,81235-32-7
acetylacetone

: 52328-96-8
bis-demethoxycurcumin

Guidance literature:: acetylacetone; With boron trioxide; In ethyl acetate; at 80 ℃; for 0.5h;

4-hydroxy-benzaldehyde; With boric acid tributyl ester; In ethyl acetate; at 80 ℃; for 0.5h; Further stages;
DOI:10.1021/acs.jmedchem.5b00894