ETHYL 3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE

Base Information

• Chemical Name: ETHYL 3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE
• CAS No.: 52505-56-3
• Molecular Formula: C12H14 N2 O2 S
• Molecular Weight: 250.321
• Hs Code.: 2934999090
• Mol file: 52505-56-3.mol

Synonyms:3-Amino-2-carbethoxy-4,6-dimethylthieno[2,3-b]pyridine;3-Amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylic acid ethyl ester; NSC339676

Chemical Property of ETHYL 3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE

Chemical Property:

• Vapor Pressure: 9.72E-07mmHg at 25°C
• Boiling Point: 404.1°Cat760mmHg
• Flash Point: 198.2°C
• PSA: 93.45000
• Density: 1.28g/cm³
• LogP: 3.25320

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl3-Amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Ethyl 3-Amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate is an intermediate in preparation of 2-[[4-(Arylazo)-3,5-disubstituted-pyrazol-1-yl]carbonyl]thieno[2,3-b]pyridine dyes for polyamide and polyester fibers.

Technology Process of ETHYL 3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE

There total 12 articles about ETHYL 3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4,6-Dimethyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile (54585-47-6) + chloroacetic acid ethyl ester (105-39-5) → ethyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate (52505-56-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 4h; Ambient temperature;

Reference yield: 96.0%

→ ethyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate (52505-56-3)

Guidance literature:

Reference yield: 95.0%

2-(3-Cyano-4,6-dimethyl)pyridyl (ethoxycarbonyl)methyl sulfide (128257-06-7) → ethyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate (52505-56-3)

Guidance literature:

With sodium ethanolate; In ethanol; for 0.25h; Heating;

upstream raw materials:

2-chloro-4,6-dimethylnicotinonitrile

ethyl 2-sulfanylacetate

3-cyano-4,6-dimethyl-2-mercaptopyridine

chloroacetic acid ethyl ester

Downstream raw materials:

7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidine-4(1H)-one

4-Chlor-7,9-dimethyl-2-phenyl-pyrido<3',2':4,5>thieno<3,2-d>pyrimidin

2-(7,9-Dimethyl-2-phenyl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-ylamino)-ethanol

6,8-Dimethyl-4-phenyl-2,3-dihydro-10-thia-1,3a,5,9-tetraaza-cyclopenta[a]fluorene