1-Pyrrolidinecarboxylic acid, 2-[(1S,2S)-3-(3,5-difluorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy] -2-[[3-(methoxycarbonyl)benzoyl]amino]propyl]-4-propoxy-, 1,1-dimethylethyl ester, (2R,4R)-

Base Information

Chemical Name:1-Pyrrolidinecarboxylic acid, 2-[(1S,2S)-3-(3,5-difluorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy] -2-[[3-(methoxycarbonyl)benzoyl]amino]propyl]-4-propoxy-, 1,1-dimethylethyl ester, (2R,4R)-
CAS No.:910447-83-5
Molecular Formula:C36H52F2N2O7Si
Molecular Weight:690.9
Hs Code.:

1-Pyrrolidinecarboxylic acid,
2-[(1S,2S)-3-(3,5-difluorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]
-2-[[3-(methoxycarbonyl)benzoyl]amino]propyl]-4-propoxy-,
1,1-dimethylethyl ester, (2R,4R)-

Synonyms:

Suppliers and Price of 1-Pyrrolidinecarboxylic acid, 2-[(1S,2S)-3-(3,5-difluorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy] -2-[[3-(methoxycarbonyl)benzoyl]amino]propyl]-4-propoxy-, 1,1-dimethylethyl ester, (2R,4R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-Pyrrolidinecarboxylic acid, 2-[(1S,2S)-3-(3,5-difluorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy] -2-[[3-(methoxycarbonyl)benzoyl]amino]propyl]-4-propoxy-, 1,1-dimethylethyl ester, (2R,4R)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Pyrrolidinecarboxylic acid, 2-[(1S,2S)-3-(3,5-difluorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy] -2-[[3-(methoxycarbonyl)benzoyl]amino]propyl]-4-propoxy-, 1,1-dimethylethyl ester, (2R,4R)-

There total 1 articles about 1-Pyrrolidinecarboxylic acid, 2-[(1S,2S)-3-(3,5-difluorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy] -2-[[3-(methoxycarbonyl)benzoyl]amino]propyl]-4-propoxy-, 1,1-dimethylethyl ester, (2R,4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 910447-82-4
(2R,4R)-tert-butyl 2-((1S,2S)-2-amino-1-(tert-butyldimethylsilyloxy)-3-(3,5-difluorophenyl)propyl)-4-propoxypyrrolidine-1-carboxylate

: 1877-71-0
benzene 1,3-dicarboxylic acid monomethyl ester

: 910447-83-5
(2R,4R)-tert-butyl 2-((1S,2S)-1-(tert-butyldimethylsilyloxy)-3-(3,5-difluorophenyl)-2-(3-(methoxycarbonyl)benzamido)propyl)-4-propoxypyrrolidine-1-carboxylate

Guidance literature:: benzene 1,3-dicarboxylic acid monomethyl ester; With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; N,N-dimethyl-formamide; for 0.333333h;

(2R,4R)-tert-butyl 2-((1S,2S)-2-amino-1-(tert-butyldimethylsilyloxy)-3-(3,5-difluorophenyl)propyl)-4-propoxypyrrolidine-1-carboxylate; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 910447-83-5
(2R,4R)-tert-butyl 2-((1S,2S)-1-(tert-butyldimethylsilyloxy)-3-(3,5-difluorophenyl)-2-(3-(methoxycarbonyl)benzamido)propyl)-4-propoxypyrrolidine-1-carboxylate

: 910447-84-6
3-(((1S,2S)-1-((2R,4R)-1-(tert-butoxycarbonyl)-4-propoxypyrrolidin-2-yl)-1-(tert-butyldimethylsilyloxy)-3-(3,5-difluorophenyl)propan-2-yl)carbamoyl)benzoic acid

Guidance literature:: (2R,4R)-tert-butyl 2-((1S,2S)-1-(tert-butyldimethylsilyloxy)-3-(3,5-difluorophenyl)-2-(3-(methoxycarbonyl)benzamido)propyl)-4-propoxypyrrolidine-1-carboxylate; With methanol; lithium hydroxide; water; at 20 ℃; for 24h;

With hydrogenchloride; water; In methanol; diethyl ether;