1-Ethyl-6-methoxy-2-(4-methoxyphenyl)-1H-indole

Base Information

Chemical Name:1-Ethyl-6-methoxy-2-(4-methoxyphenyl)-1H-indole
CAS No.:91444-19-8
Molecular Formula:C18H19NO2
Molecular Weight:281.354
Hs Code.:
DSSTox Substance ID:DTXSID70539837
Wikidata:Q82415646

Synonyms:91444-19-8;1-Ethyl-6-methoxy-2-(4-methoxyphenyl)-1H-indole;SCHEMBL7942901;DTXSID70539837

Suppliers and Price of 1-Ethyl-6-methoxy-2-(4-methoxyphenyl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Chemical Property of 1-Ethyl-6-methoxy-2-(4-methoxyphenyl)-1H-indole

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:281.141578849
Heavy Atom Count:21
Complexity:327

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C(=CC2=C1C=C(C=C2)OC)C3=CC=C(C=C3)OC

Technology Process of 1-Ethyl-6-methoxy-2-(4-methoxyphenyl)-1H-indole

There total 5 articles about 1-Ethyl-6-methoxy-2-(4-methoxyphenyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62655-56-5
2-(4'-methoxy-phenyl)-6-methoxy-indole

: 75-03-6
ethyl iodide

: 91444-19-8
1-ethyl-2-(4-methoxyphenyl)-6-methoxyindole

Guidance literature:: With ammonia; sodium; Multistep reaction; 1.) THF, -70 deg C, 30 min, 2.) THF, -70 deg C, 30 min;
DOI:10.1021/jm00377a011

Reference yield:

: 536-90-3,918666-97-4
m-Anisidine

: 91444-19-8
1-ethyl-2-(4-methoxyphenyl)-6-methoxyindole

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethylaniline / 170 °C

2: 1.) Na/liquid NH₃ / 1.) THF, -70 deg C, 30 min, 2.) THF, -70 deg C, 30 min

With ammonia; sodium; N,N-dimethyl-aniline;
DOI:10.1021/jm00377a011

Reference yield:

: 2632-13-5
2-Bromo-4'-methoxyacetophenone

: 91444-19-8
1-ethyl-2-(4-methoxyphenyl)-6-methoxyindole

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethylaniline / 170 °C

2: 1.) Na/liquid NH₃ / 1.) THF, -70 deg C, 30 min, 2.) THF, -70 deg C, 30 min

With ammonia; sodium; N,N-dimethyl-aniline;
DOI:10.1021/jm00377a011