5-(2-Chlorophenyl)furan-2-carboxylic acid

Base Information

Chemical Name:5-(2-Chlorophenyl)furan-2-carboxylic acid
CAS No.:41019-43-6
Molecular Formula:C11H7ClO3
Molecular Weight:222.628
Hs Code.:2932190090
European Community (EC) Number:664-378-4
UNII:L5RCO4YA70
DSSTox Substance ID:DTXSID60354834
Nikkaji Number:J2.111.074D
Wikidata:Q27093893
Metabolomics Workbench ID:147459
ChEMBL ID:CHEMBL200238
Mol file:41019-43-6.mol

Synonyms:5-(2-CHLOROPHENYL)FURAN-2-CARBOXYLIC ACID;41019-43-6;5-(2-chlorophenyl)-2-furoic acid;PD042182;L5RCO4YA70;5-(2-Chloro-phenyl)-furan-2-carboxylic acid;5-(2-Chlorophenyl)-2-furancarboxylic acid;UNII-L5RCO4YA70;PD-042182;CHEMBL200238;MFCD02625435;1xnz;MLS000058465;cid_784625;SCHEMBL4987351;DTXSID60354834;HMS2335G24;HMS3604B11;KUC100867N;KUC100895N;AMY20958;BBL012047;BDBM50175442;STK075695;AKOS000443135;DB02909;NCGC00041402-02;PD007963;SMR000067914;BB 0222509;CS-0095219;FT-0759208;EN300-12246;A20420;MLS-0026646.0001;J-516101;Q27093893;Z57727894

Suppliers and Price of 5-(2-Chlorophenyl)furan-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(2-Chlorophenyl)furan-2-carboxylicAcid
500mg
$ 60.00

TRC
5-(2-Chlorophenyl)furan-2-carboxylicAcid
100mg
$ 45.00

Sigma-Aldrich
5-(2-CHLOROPHENYL)-2-FUROIC ACID Aldrich
1g
$ 144.00

Crysdot
5-(2-Chlorophenyl)furan-2-carboxylicacid 95+%
1g
$ 432.00

CHESS?
CA051014:5-(2-Chloro-phenyl)-furan-2-carboxylicacid 97
1 g
$ 90.00

Chemenu
5-(2-Chlorophenyl)furan-2-carboxylicacid 95%
1g
$ 408.00

ChemBridge Corporation
5-(2-CHLOROPHENYL)-2-FUROIC ACID 95%
1 g
$ 23.00

American Custom Chemicals Corporation
5-(2-CHLOROPHENYL)-2-FUROIC ACID 95.00%
5G
$ 1114.58

American Custom Chemicals Corporation
5-(2-CHLOROPHENYL)-2-FUROIC ACID 95.00%
2.5G
$ 932.60

American Custom Chemicals Corporation
5-(2-CHLOROPHENYL)-2-FUROIC ACID 95.00%
1G
$ 692.46

Total 20 raw suppliers

Chemical Property of 5-(2-Chlorophenyl)furan-2-carboxylic acid

Chemical Property:

Vapor Pressure:2.49E-06mmHg at 25°C
Melting Point:167-168 °C(Solv: dichloromethane (75-09-2))
Refractive Index:1.594
Boiling Point:376.3 °C at 760 mmHg
PKA:2.99±0.10(Predicted)
Flash Point:181.4 °C
PSA：50.44000
Density:1.374 g/cm³
LogP:3.29820
Storage Temp.:2-8°C
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:222.0083718
Heavy Atom Count:15
Complexity:244

Purity/Quality:

97% ^*data from raw suppliers

5-(2-Chlorophenyl)furan-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=CC=C(O2)C(=O)O)Cl

Technology Process of 5-(2-Chlorophenyl)furan-2-carboxylic acid

There total 6 articles about 5-(2-Chlorophenyl)furan-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 41019-38-9
5-(2-chlorophenyl)furan-2-carboxylic acid methyl ester

: 41019-43-6
5-(2-chlorophenyl)-2-furoic acid

Guidance literature:: With potassium hydroxide; In ethanol; for 0.5h; Reflux;
DOI:10.1134/S1070428009040125

Reference yield: 53.0%

: 88-14-2
2-furanoic acid

: 95-51-2
o-chloroaniline

: 41019-43-6
5-(2-chlorophenyl)-2-furoic acid

Guidance literature:: o-chloroaniline; With hydrogenchloride; sodium nitrite; at 0 - 5 ℃; for 0.5h;

2-furanoic acid; With copper dichloride; In water; at 20 ℃;
DOI:10.1002/jccs.200400151

Reference yield:

: 3900-89-8
2-Chlorobenzeneboronic acid

: 41019-43-6
5-(2-chlorophenyl)-2-furoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,4-dioxane / 5 h / 100 °C

2: sodium hydroxide / methanol / 0.5 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; sodium hydroxide; In 1,4-dioxane; methanol; 1: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2018.12.058