Methyl 5-(2-chlorophenyl)furan-2-carboxylate

Base Information

Chemical Name:Methyl 5-(2-chlorophenyl)furan-2-carboxylate
CAS No.:41019-38-9
Molecular Formula:C12H9ClO3
Molecular Weight:236.655
Hs Code.:2932190090
ChEMBL ID:CHEMBL200770
DSSTox Substance ID:DTXSID70463047
Wikidata:Q82287773
Mol file:41019-38-9.mol

Synonyms:Methyl 5-(2-chlorophenyl)furan-2-carboxylate;41019-38-9;5-(2-CHLOROPHENYL)FURAN-2-CARBOXYLIC ACID METHYL ESTER;CHEMBL200770;SCHEMBL4942886;DTXSID70463047;BDBM50175457;AKOS008762677;FT-0754644;METHYL 5-(2-CHLOROPHENYL)-2-FUROATE

Suppliers and Price of Methyl 5-(2-chlorophenyl)furan-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
METHYL 5-(2-CHLOROPHENYL)-2-FUROATE Aldrich
1g
$ 144.00

American Custom Chemicals Corporation
5-(2-CHLOROPHENYL)FURAN-2-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 500.83

Total 0 raw suppliers

Chemical Property of Methyl 5-(2-chlorophenyl)furan-2-carboxylate

Chemical Property:

PSA：39.44000
LogP:3.38660
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:236.0240218
Heavy Atom Count:16
Complexity:257

Purity/Quality:: METHYL 5-(2-CHLOROPHENYL)-2-FUROATE Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=C(O1)C2=CC=CC=C2Cl

Technology Process of Methyl 5-(2-chlorophenyl)furan-2-carboxylate

There total 10 articles about Methyl 5-(2-chlorophenyl)furan-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 2527-99-3
methyl 5-bromo-2-furoate

: 3900-89-8
2-Chlorobenzeneboronic acid

: 41019-38-9
5-(2-chlorophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In 1,4-dioxane; at 90 ℃; Inert atmosphere;
DOI:10.1016/j.ejmech.2018.06.033

Reference yield: 56.0%

: 611-13-2
2-furoic acid methyl ester

: 95-51-2
o-chloroaniline

: 41019-38-9
5-(2-chlorophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: o-chloroaniline; With hydrogenchloride; sodium nitrite;

2-furoic acid methyl ester; With copper(II) chloride dihydrate; In water; acetone; at 0 - 30 ℃;
DOI:10.1134/S1070428009040125

Reference yield:

: 88-14-2
2-furanoic acid

: 41019-38-9
5-(2-chlorophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaNO₂; aq. HCl

1.2: CuCl₂

With hydrogenchloride; sodium nitrite; 1.2: Meerwein arylation;
DOI:10.1016/j.bmcl.2005.09.019