(S)-2-Oxo-3-phenyloxazolidine-5-carboxylic acid

Base Information

Chemical Name:(S)-2-Oxo-3-phenyloxazolidine-5-carboxylic acid
CAS No.:918543-49-4
Molecular Formula:C10H9NO4
Molecular Weight:207.186
Hs Code.:
DSSTox Substance ID:DTXSID00582391
Wikidata:Q82473805

Synonyms:918543-49-4;(S)-2-Oxo-3-phenyloxazolidine-5-carboxylic acid;SCHEMBL4669702;DTXSID00582391;(5S)-2-Oxo-3-phenyl-1,3-oxazolidine-5-carboxylic acid

Suppliers and Price of (S)-2-Oxo-3-phenyloxazolidine-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (S)-2-Oxo-3-phenyloxazolidine-5-carboxylic acid

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:207.05315777
Heavy Atom Count:15
Complexity:273

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OC(=O)N1C2=CC=CC=C2)C(=O)O
Isomeric SMILES:C1[C@H](OC(=O)N1C2=CC=CC=C2)C(=O)O

Technology Process of (S)-2-Oxo-3-phenyloxazolidine-5-carboxylic acid

There total 4 articles about (S)-2-Oxo-3-phenyloxazolidine-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 99827-73-3
(S)-5-(hydroxymethyl)-3-phenyloxazolidin-2-one

: 918543-49-4
(S)-2-oxo-3-phenyloxazolidine-5-carboxylic acid

Guidance literature:: With sodium periodate; ruthenium(III) trichloride hydrate; In tetrachloromethane; water; acetonitrile; at 0 ℃; Inert atmosphere;

Reference yield:

: 3422-02-4
N-(benzyloxycarbonyl)aniline

: 918543-49-4
(S)-2-oxo-3-phenyloxazolidine-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 0.75 h / -78 °C

1.2: tetrahydrofuran; hexane / -78 - 20 °C

2.1: NaIO₄; RuCl₃*H₂O / acetonitrile; CCl₄ / 0 - 20 °C

With ruthenium trichloride; sodium periodate; n-butyllithium; In tetrahydrofuran; tetrachloromethane; hexane; acetonitrile;
DOI:10.1021/jm060666p

Reference yield:

: 62-53-3
aniline

: 918543-49-4
(S)-2-oxo-3-phenyloxazolidine-5-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaHCO₃ / acetone; H₂O / 20 °C

2.1: n-BuLi / tetrahydrofuran; hexane / 0.75 h / -78 °C

2.2: tetrahydrofuran; hexane / -78 - 20 °C

3.1: NaIO₄; RuCl₃*H₂O / acetonitrile; CCl₄ / 0 - 20 °C

With ruthenium trichloride; sodium periodate; n-butyllithium; sodium hydrogencarbonate; In tetrahydrofuran; tetrachloromethane; hexane; water; acetone; acetonitrile;
DOI:10.1021/jm060666p