1-[2-deoxy-5-O-(phenoxycarbonyl)pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione

Base Information

Chemical Name:1-[2-deoxy-5-O-(phenoxycarbonyl)pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione
CAS No.:5864-33-5
Molecular Formula:C17H18 N2 O7
Molecular Weight:362.334
Hs Code.:

Synonyms:Carbonicacid, phenyl ester, 5'-ester with thymidine (8CI);NSC 211721

Suppliers and Price of 1-[2-deoxy-5-O-(phenoxycarbonyl)pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 9 raw suppliers

Chemical Property of 1-[2-deoxy-5-O-(phenoxycarbonyl)pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.406g/cm³

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[2-deoxy-5-O-(phenoxycarbonyl)pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione

There total 2 articles about 1-[2-deoxy-5-O-(phenoxycarbonyl)pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: acetone O-((phenyloxy)carbonyl) oxime

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine

: 5864-33-5
5'-O-Carbophenoxythymidine

Guidance literature:: In tetrahydrofuran; at 60 ℃; for 36h; lipase from C_. antarctica;
DOI:10.1021/jo9606259

Reference yield: 60.0%

: 1885-14-9
phenyl chloroformate

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine

: 5864-33-5
5'-O-Carbophenoxythymidine

Guidance literature:: With pyridine;
DOI:10.1021/ja030376n

Reference yield:

: 5864-33-5
5'-O-Carbophenoxythymidine

: 182126-65-4
1-((4aS,6R,7aR)-1-Benzyl-2-oxo-hexahydro-furo[3,2-d][1,3]oxazin-6-yl)-5-methyl-1H-pyrimidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) pyridine / 1.) THF, reflux, 2.) overnight

2: 70 percent / NaH / tetrahydrofuran / 1.) 0 deg C, 2 h, 2.) room temperature, 20 h

With pyridine; sodium hydride; In tetrahydrofuran;
DOI:10.1021/jo9606259