1-Piperidinecarboxylic acid, 4-[4-(methylsulfonyl)phenyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:1-Piperidinecarboxylic acid, 4-[4-(methylsulfonyl)phenyl]-, 1,1-dimethylethyl ester
CAS No.:918884-56-7
Molecular Formula:C17H25NO4S
Molecular Weight:339.456
Hs Code.:

Synonyms:4-(4-methanesulfonylphenyl)piperidine-1-carboxylic acid tert-butyl ester;

Suppliers and Price of 1-Piperidinecarboxylic acid, 4-[4-(methylsulfonyl)phenyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
tert-Butyl4-(4-(methylsulfonyl)phenyl)piperidine-1-carboxylate 97%
1g
$ 450.00

Total 0 raw suppliers

Chemical Property of 1-Piperidinecarboxylic acid, 4-[4-(methylsulfonyl)phenyl]-, 1,1-dimethylethyl ester

Chemical Property:

Boiling Point:485.2±45.0 °C(Predicted)
PSA：72.06000
Density:1.167±0.06 g/cm3(Predicted)
LogP:4.22330

Purity/Quality:: tert-Butyl4-(4-(methylsulfonyl)phenyl)piperidine-1-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Piperidinecarboxylic acid, 4-[4-(methylsulfonyl)phenyl]-, 1,1-dimethylethyl ester

There total 6 articles about 1-Piperidinecarboxylic acid, 4-[4-(methylsulfonyl)phenyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 732275-87-5
tert-butyl 4-[4-(methylthio)phenyl]piperidine-1-carboxylate

: 918884-56-7
tert-butyl 4-(4-(methylsulfonyl)phenyl)piperidine-1-carboxylate

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 2.5h;

Reference yield: 76.0%

: 3466-32-8
4-bromoohenyl methyl sulfone

: 1-(1-(tert-butoxycarbonyl)piperidin-4-yl)-2,4,6-triphenylpyridin-1-ium tetrafluoroborate

: 918884-56-7
tert-butyl 4-(4-(methylsulfonyl)phenyl)piperidine-1-carboxylate

Guidance literature:: With nickel(II) bromide diethylene glycol dimethyl ether; 4,4'-Dimethoxy-2,2'-bipyridin; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; In N,N-dimethyl acetamide; at 20 ℃; for 16h; Irradiation;
DOI:10.1021/acscatal.1c01416

Reference yield: 70.0%

: 3466-32-8
4-bromoohenyl methyl sulfone

: 2-((1-(tert-butoxycarbonyl)piperidin-4-yl)oxy)-2-oxoacetic acid

: 918884-56-7
tert-butyl 4-(4-(methylsulfonyl)phenyl)piperidine-1-carboxylate

Guidance literature:: With cesium bicarbonate; [Ir(dF(H)ppy)₂(dtbbpy)](PF₆); 4,4'-di-tert-butyl-2,2'-bipyridine nickel(II) bromide; In 1,4-dioxane; dimethyl sulfoxide; at 80 ℃; for 4h; Inert atmosphere; Irradiation;
DOI:10.1021/jacs.6b09533