Carvedilol Bis-carbazole

Base Information

Chemical Name:Carvedilol Bis-carbazole
CAS No.:918903-20-5
Molecular Formula:C39H39N3O6
Molecular Weight:645.755
Hs Code.:2933997500
Mol file:918903-20-5.mol

Synonyms:3,3'-[2-(2-Methoxyphenoxy)ethylazanediyl]bis[1-(9H-carbazol-4-yloxy)propan-2-ol];Carvedilol Bis-carbazole;Carvedilol Related Compound B;UNII-56RX0K2UL0;

Suppliers and Price of Carvedilol Bis-carbazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
CarvedilolBis-carbazole
1g
$ 1680.00

Sigma-Aldrich
Carvedilol Related Compound B United States Pharmacopeia (USP) Reference Standard
15mg
$ 1260.00

Biosynth Carbosynth
Carvedilol bis-carbazole
10 mg
$ 1850.00

Biosynth Carbosynth
Carvedilol bis-carbazole
5 mg
$ 1275.00

American Custom Chemicals Corporation
CARVEDILOL BIS-CARBAZOLE 95.00%
1MG
$ 721.88

American Custom Chemicals Corporation
CARVEDILOL BIS-CARBAZOLE 95.00%
10MG
$ 1963.50

AK Scientific
3,3'-(2-(2-Methoxyphenoxy)ethylazanediyl)bis(1-(9H-carbazol-4-yloxy)propan-2-ol)
10mg
$ 2547.00

Total 13 raw suppliers

Chemical Property of Carvedilol Bis-carbazole

Chemical Property:

Melting Point:>143°C (dec.)
Boiling Point:905.6oC at 760 mmHg
PKA:13.53±0.20(Predicted)
Flash Point:501.5oC
PSA：112.20000
Density:1.328g/cm3
LogP:6.52480
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Very Slight

Purity/Quality:

99%, ^*data from raw suppliers

CarvedilolBis-carbazole ^*data from reagent suppliers

Safty Information:

Pictogram(s): 14441019
Hazard Codes:N
Statements: 51/53
Safety Statements: 61

MSDS Files:: SDS file from LookChem

Useful:

Uses An impurity from the process of Carvedilol. Carvedilol impurity B An impurity from the process of Carvedilol (C184625). Carvedilol impurity B. Carvedilol Bis-carbazole (Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B) is an impurity from the process of Carvedilol (C184625).

Technology Process of Carvedilol Bis-carbazole

There total 5 articles about Carvedilol Bis-carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.21%

: 787598-91-8
(+/-)-1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)-ethyl]-amino]-2-propanol salicylate

: 918903-20-5
C₃₉H₃₉N₃O₆

: 72956-09-3
carvedilol

Guidance literature:: With sodium hydroxide; In water; isopropyl alcohol; at 50 - 70 ℃; for 0.75h;

Reference yield: 58.0%

: 1836-62-0
2-(2-methoxy-phenoxy)-ethylamine

: 51997-51-4,95093-96-2
4-(2,3-epoxypropoxy)carbazole

: 918903-20-5
C₃₉H₃₉N₃O₆

: 72956-09-3
carvedilol

Guidance literature:: In dimethyl sulfoxide; at 68 - 72 ℃; for 18 - 20h;

Reference yield: 57.0%

: 1836-62-0
2-(2-methoxy-phenoxy)-ethylamine

: 69-72-7,25496-36-0,8052-31-1
salicylic acid

: 51997-51-4,95093-96-2
4-(2,3-epoxypropoxy)carbazole

: 787598-91-8
(+/-)-1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)-ethyl]-amino]-2-propanol salicylate

: 918903-20-5
C₃₉H₃₉N₃O₆

Guidance literature:: 2-(2-methoxy-phenoxy)-ethylamine; 4-(2,3-epoxypropoxy)carbazole; In isopropyl alcohol; at 70 - 85 ℃; for 1h; Heating / reflux;

salicylic acid; In isopropyl alcohol; at 50 - 85 ℃; for 3h; Product distribution / selectivity; Heating / reflux;