N-(Benzylideneamino)-4-methoxy-benzamide

Base Information

• Chemical Name: N-(Benzylideneamino)-4-methoxy-benzamide
• CAS No.: 51651-81-1
• Molecular Formula: C15H14N2O2
• Molecular Weight: 254.288
• European Community (EC) Number: 660-320-7
• DSSTox Substance ID: DTXSID50295626
• Mol file: 51651-81-1.mol

Synonyms:N-(benzylideneamino)-4-methoxybenzamide;51651-81-1;N//'-Benzylidene-4-methoxybenzohydrazide;N-(BENZYLIDENEAMINO)-4-METHOXY-BENZAMIDE;SCHEMBL20299346;DTXSID50295626;AKOS030657879;N-benzylidene-N'-(4-methoxybenzoyl)hydrazine

Chemical Property of N-(Benzylideneamino)-4-methoxy-benzamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.1g/cm³
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 254.105527694
• Heavy Atom Count: 19
• Complexity: 303

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=O)NN=CC2=CC=CC=C2

Technology Process of N-(Benzylideneamino)-4-methoxy-benzamide

There total 4 articles about N-(Benzylideneamino)-4-methoxy-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-methoxybenzoic acid hydrazide (3290-99-1) + benzaldehyde (100-52-7) → N-benzaldehyde(p-methoxybenzoylhydrazone) (51651-81-1)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; dimethyl sulfoxide; at 20 ℃;

DOI:10.1016/j.bmc.2020.115710

Reference yield:

4-methoxybenzoic acid hydrazide (3290-99-1) → N-benzaldehyde(p-methoxybenzoylhydrazone) (51651-81-1)

Guidance literature:

With benzaldehyde;

Reference yield:

4-methoxy-benzoyl chloride (100-07-2) → N-benzaldehyde(p-methoxybenzoylhydrazone) (51651-81-1)

Guidance literature:

Multi-step reaction with 2 steps

1: diluted KOH-solution; hydrazine sulfate

2: benzaldehyde

With potassium hydroxide; benzaldehyde; hydrazinium sulfate;

upstream raw materials:

4-methoxybenzoic acid hydrazide

benzaldehyde

4-methoxy-benzoyl chloride

Downstream raw materials:

1-chloro-1-(4-methoxyphenyl)-4-phenyl-2,3-diazabutadiene

trans-[Ru(III)(C₆H₄CHNNC(4-MeO-C₆H₄)O)(PPh₃)2Cl]

2-(4-methoxy-phenyl)-5-phenyl-[1,3,4]oxadiazole

N-(2,2-difluoro-3-oxo-1,3-diphenylpropyl)-4-methoxybenzohydrazide