1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate

Base Information

Chemical Name:1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate
CAS No.:158275-79-7
Molecular Formula:C₁₅H₂₈O₇Si
Molecular Weight:348.469
Hs Code.:2931900090
Mol file:158275-79-7.mol

Synonyms:R-(-)-3-(tert-Butyldimethylsilyloxy)glutaricacid monomethyl ester monoethyl carbonate anhydride;

Suppliers and Price of 1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate 95+%
1g
$ 1210.00

Matrix Scientific
1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate 95+%
250mg
$ 545.00

Crysdot
1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate 95+%
1g
$ 564.00

Chemenu
1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate 95%
1g
$ 533.00

American Custom Chemicals Corporation
1-ETHOXYCARBONYL-5-METHYL-(3R)-3-TERT-BUTYL-DIMETHYLSILYLOXYPENTANEDIOATE 95.00%
1G
$ 1185.45

AK Scientific
1,5-Ethoxycarbonylmethyl-(3r)-3-tert-butyl-dimethylsilyloxypentanedioate
1g
$ 1683.00

Total 53 raw suppliers

Chemical Property of 1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate

Chemical Property:

Vapor Pressure:1.51E-05mmHg at 25°C
Refractive Index:1.443
Boiling Point:366 °C at 760 mmHg
Flash Point:145.5 °C
PSA：88.13000
Density:1.058 g/cm³
LogP:3.02970
Storage Temp.:2-8°C

Purity/Quality:

99% ^*data from raw suppliers

1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate

There total 7 articles about 1-Ethoxycarbonyl-5-methyl-(3R)-3-tert-butyl-dimethylsilyloxypentanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 541-41-3
chloroformic acid ethyl ester

: 109744-49-2
Hydrogen (3R)-1-methyl 3-<(tert-butyldimethylsilyl)oxy>pentanedioate

: 1350364-18-9,158275-79-7
C₁₅H₂₈O₇Si

Guidance literature:: With triethylamine; In hexane; at -40 ℃; for 3h;

Reference yield:

: 91424-40-7
3-(tert-butyldimethylsilyloxy)glutaric anhydride

: 1350364-18-9,158275-79-7
C₁₅H₂₈O₇Si

Guidance literature:: Multi-step reaction with 4 steps

1.1: n-butyllithium; triphenylmethane; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol / toluene; hexane; tetrahydrofuran / 2 h / -78 °C

1.2: 3 h

2.1: hydrogen / palladium 10% on activated carbon / ethyl acetate

3.1: sodium methylate / 3 h / 0 - 5 °C / Cooling with ice

3.3: pH 6.5

4.1: triethylamine / hexane / 3 h / -40 °C

With n-butyllithium; triphenylmethane; hydrogen; sodium methylate; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol; triethylamine; palladium 10% on activated carbon; In tetrahydrofuran; hexane; ethyl acetate; toluene;

Reference yield:

: (3R)-3-<(tert-Butyldimethylsilyl)oxy>pentanedioic acid 1- ester

: 1350364-18-9,158275-79-7
C₁₅H₂₈O₇Si

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogen / palladium 10% on activated carbon / ethyl acetate

2.1: sodium methylate / 3 h / 0 - 5 °C / Cooling with ice

2.3: pH 6.5

3.1: triethylamine / hexane / 3 h / -40 °C

With hydrogen; sodium methylate; triethylamine; palladium 10% on activated carbon; In hexane; ethyl acetate;