O(6)-Ethyl-2'-deoxyguanosine

Base Information

• Chemical Name: O(6)-Ethyl-2'-deoxyguanosine
• CAS No.: 50704-46-6
• Molecular Formula: C₁₂H₁₇N₅O₄
• Molecular Weight: 295.298
• UNII: UG1B1H0FL4
• Nikkaji Number: J482.516K
• Wikidata: Q27130565
• Metabolomics Workbench ID: 61395
• Mol file: 50704-46-6.mol

Synonyms:2'-deoxy-O(6)-ethylguanosine;O(6)-ethyl-2'-deoxyguanosine;O(6)-ethyldeoxyguanosine

Chemical Property of O(6)-Ethyl-2'-deoxyguanosine

Chemical Property:

• Vapor Pressure: 1.16E-18mmHg at 25°C
• Boiling Point: 666.3°C at 760 mmHg
• Flash Point: 356.8°C
• PSA: 128.54000
• Density: 1.75g/cm³
• LogP: 0.02910
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 4
• Exact Mass: 295.12805404
• Heavy Atom Count: 21
• Complexity: 363

Purity/Quality:

97% ^*data from raw suppliers

O6-Ethyl-2’-deoxyguanosine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=NC(=NC2=C1N=CN2C3CC(C(O3)CO)O)N
• Isomeric SMILES: CCOC1=NC(=NC2=C1N=CN2[C@H]3C[C@@H]([C@H](O3)CO)O)N
• Uses: O6-Ethyl-2’-deoxyguanosine exists due to a mutation occurring in guanine. It is a genotoxic compound which has been identified as a carcinogenic compound.

Technology Process of O(6)-Ethyl-2'-deoxyguanosine

There total 18 articles about O(6)-Ethyl-2'-deoxyguanosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2'-deoxy-O6-ethyl-N2-isobutyrylguanosine (82921-46-8) → 2'-deoxy-O6-ethylguanosine (50704-46-6)

Guidance literature:

With ammonium hydroxide; at 50 ℃; for 72h;

DOI:10.1016/S0040-4039(00)87314-1

Reference yield: 83.0%

sodium ethanolate (141-52-6) + 2-amino-6-chloro-9-[(3’,5’-di-O-acetyl-2’-deoxy)-β-D-ribofuranosyl]purine (69992-11-6) → 2'-deoxy-O6-ethylguanosine (50704-46-6)

Guidance literature:

In ethanol; Reflux;

DOI:10.1002/anie.201511520

Reference yield: 79.0%

9-[2-deoxy-3,5-di-O-(4-toluoyl)-β-D-erythro-pentafuranosyl]-6-ethoxy-9H-purin-2-amine → 2'-deoxy-O6-ethylguanosine (50704-46-6)

Guidance literature:

With sodium methylate; In methanol; for 0.5h; Ambient temperature;

DOI:10.1002/hlca.19970800424

upstream raw materials:

2'-deoxy-O⁶-ethyl-N²-isobutyrylguanosine

(2R,3S,5R)-5-(2-Amino-6-ethoxy-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-ol

2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride

NU₂₀₄₆

Downstream raw materials:

2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N²-isobutyryl-O⁶-ethylguanosine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 50704-46-6 O(6)-ethyl-2'-deoxyguanosine

Send

Send

Metric Ton KG G Pound L ML

Send

Send