1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 4-chloro-1-(phenylsulfonyl)-

Base Information

Chemical Name:1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 4-chloro-1-(phenylsulfonyl)-
CAS No.:920965-86-2
Molecular Formula:C14H8ClN3O2S
Molecular Weight:317.755
Hs Code.:
Mol file:920965-86-2.mol

Synonyms:4-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile;1H-PYRROLO[2,3-B]PYRIDINE-3-CARBONITRILE,4-CHLORO-1-(PHENYLSULFONYL);

Suppliers and Price of 1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 4-chloro-1-(phenylsulfonyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-CHLORO-1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBONITRILE 95.00%
5MG
$ 505.82

Total 1 raw suppliers

Chemical Property of 1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 4-chloro-1-(phenylsulfonyl)-

Chemical Property:

Vapor Pressure:5.46E-12mmHg at 25°C
Boiling Point:546.3oC at 760 mmHg
Flash Point:284.2oC
PSA：84.13000
Density:1.48g/cm3
LogP:3.87918

Purity/Quality:: 4-CHLORO-1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 4-chloro-1-(phenylsulfonyl)-

There total 2 articles about 1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 4-chloro-1-(phenylsulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 920965-87-3
4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile

: 98-09-9
benzenesulfonyl chloride

: 920965-86-2
1-(benzenesulfonyl)-4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃; for 3.5h; Inert atmosphere;

Reference yield:

: 920966-51-4
3-bromo-4-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

: 557-21-1
dicyanozinc

: 920965-86-2
1-(benzenesulfonyl)-4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile

Guidance literature:: tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,3-dimethyl-2-imidazolidinone; at 20 - 140 ℃; for 1.5h;

Reference yield: 75.0%

: 920965-86-2
1-(benzenesulfonyl)-4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile

: 398151-59-2
(4-formyl-3-methylphenyl)boronic acid

: 1-(benzenesulfonyl)-4-(4-formyl-3-methylphenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile

Guidance literature:: With dichloro[1,1′-bis[bis(1,1-dimethylethyl)phosphino]ferrocene-P,P′]palladium; potassium carbonate; In tetrahydrofuran; water; at 100 ℃; for 1h; Inert atmosphere; Microwave irradiation;