Benzenepropanoic acid, b-hydroxy-b-(1-methylethyl)-, ethyl ester

Base Information

• Chemical Name: Benzenepropanoic acid, b-hydroxy-b-(1-methylethyl)-, ethyl ester
• CAS No.: 92301-37-6
• Molecular Formula: C14H20O3
• Molecular Weight: 236.311
• Mol file: 92301-37-6.mol

Synonyms:

Chemical Property of Benzenepropanoic acid, b-hydroxy-b-(1-methylethyl)-, ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenepropanoic acid, b-hydroxy-b-(1-methylethyl)-, ethyl ester

There total 3 articles about Benzenepropanoic acid, b-hydroxy-b-(1-methylethyl)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethyl bromoacetate (105-36-2) + phenyl isopropyl ketone (611-70-1) → (+/-)-Ethyl 3-hydroxy-4-methyl-3-phenylpentanoate (92301-37-6)

Guidance literature:

With iodine; zinc; In 1,4-dioxane; for 0.583333h; ultrasound irradiation;

DOI:10.1021/jo0261395

Reference yield:

rac-2-methyl-1-phenylpropan-1-ol (611-69-8) → (+/-)-Ethyl 3-hydroxy-4-methyl-3-phenylpentanoate (92301-37-6)

Guidance literature:

Multi-step reaction with 2 steps

1: chromic acid

2: 86 percent

With chromic acid;

Reference yield:

benzaldehyde (100-52-7) → (+/-)-Ethyl 3-hydroxy-4-methyl-3-phenylpentanoate (92301-37-6)

Guidance literature:

Multi-step reaction with 3 steps

2: chromic acid

3: 86 percent

With chromic acid;

upstream raw materials:

ethyl bromoacetate

phenyl isopropyl ketone

rac-2-methyl-1-phenylpropan-1-ol

benzaldehyde

Downstream raw materials:

(+/-) α-(RS)-Cyano-3-phenoxybenzyl-4-methyl-3-phenylpentanoate

4-methyl-3-phenylpentanoyl chloride

4-methyl-3-phenylpentanoic acid

(+/-)-ethyl 4-methyl-3-phenylpentanoate

Refernces

• 1、 Kher, S. M.,Kulkarni, G. H.. "1,2-Secopyrethroids: Synthesis of (+/-) α-(RS)-cyano-3-phenoxybenzyl-4-methyl-3-phenyl/p-substituted-phenylpentanoates". . p. 675 - 676. Retrieved 2007/10/02.