Dodecylmaleamic acid

Base Information

• Chemical Name: Dodecylmaleamic acid
• CAS No.: 52492-69-0
• Molecular Formula: C16H29 N O3
• Molecular Weight: 283.411
• Hs Code.: 2924199090
• European Community (EC) Number: 666-081-5
• Nikkaji Number: J697.594A,J1.618.705D
• Mol file: 52492-69-0.mol

Synonyms:dodecylmaleamic acid;N-dodecyl maleamic acid

Chemical Property of Dodecylmaleamic acid

Chemical Property:

• Vapor Pressure: 7.16E-10mmHg at 25°C
• Boiling Point: 463.4°Cat760mmHg
• Flash Point: 234°C
• PSA: 66.40000
• Density: 0.988g/cm³
• LogP: 4.05520
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 13
• Exact Mass: 283.21474379
• Heavy Atom Count: 20
• Complexity: 287

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCNC(=O)C=CC(=O)O
• Isomeric SMILES: CCCCCCCCCCCCNC(=O)/C=C/C(=O)O

Technology Process of Dodecylmaleamic acid

There total 3 articles about Dodecylmaleamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

maleic anhydride (108-31-6) + n-Dodecylamine (124-22-1) → (Z)-4-(dodecylamino)-4-oxobut-2-enoic acid (52492-69-0)

Guidance literature:

With toluene; at 90 ℃;

DOI:10.1021/jo01083a626

Reference yield:

n-Dodecylamine (124-22-1) + maleic acid (110-16-7,26099-09-2) → (Z)-4-(dodecylamino)-4-oxobut-2-enoic acid (52492-69-0)

Guidance literature:

In chloroform; for 0.5h;

Reference yield:

→ (Z)-4-(dodecylamino)-4-oxobut-2-enoic acid (52492-69-0)

Guidance literature:

Maleinsaeureanhydrid, Dodecylamin;

upstream raw materials:

maleic anhydride

n-Dodecylamine

maleic acid

Downstream raw materials:

n-dodecylmaleimide

Refernces

• 1、 -. "Continuous efficient production method for high-purity N-substituted maleamic acid". Paragraph 0053-0054. . Retrieved 2018/09/08.
• 2、 Grosa,Viola,Ceruti,Brusa,Delprino,Dosio,Cattel. "Synthesis and biological activity of a squalenoid maleimide and other classes of squalene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase". . p. 17 - 23. Retrieved 2007/10/02.