2-(4-methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid

Base Information

Chemical Name:2-(4-methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid
CAS No.:54001-16-0
Molecular Formula:C12H10NO3S-
Molecular Weight:249.29
Hs Code.:2934100090
European Community (EC) Number:827-427-2
DSSTox Substance ID:DTXSID60407177
Wikidata:Q82212418
Mol file:54001-16-0.mol

Synonyms:54001-16-0;2-(4-methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid;2-(4-Methoxyphenyl)-4-methylthiazole-5-carboxylic acid;MFCD06857928;SCHEMBL3419091;DTXSID60407177;HWHHZTHVYFDJNK-UHFFFAOYSA-N;AKOS000273560;AS-70916;CS-0308930;EN300-14125;D96053;2-(4-Methoxyphenyl)-4-methylthiazole-5-carboxylicacid;Z96093363;2-(4-methoxyphenyl)-4-methyl-5-thiazolecarboxylic acid;4-Methyl-2-(4-methoxyphenyl)thiazole-5-carboxylic acid;F3284-7865;2-(4-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid, AldrichCPR

Suppliers and Price of 2-(4-methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid
250mg
$ 140.00

Sigma-Aldrich
2-(4-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid Aldrich
1g
$ 135.00

Oakwood
4-Methyl-2-(4-methoxyphenyl)thiazole-5-carboxylicacid 97%
5g
$ 275.00

Matrix Scientific
2-(4-Methoxyphenyl)-4-methylthiazole-5-carboxylicacid 95%+
1g
$ 270.00

Matrix Scientific
2-(4-Methoxyphenyl)-4-methylthiazole-5-carboxylicacid 95%+
5g
$ 990.00

Crysdot
2-(4-Methoxyphenyl)-4-methylthiazole-5-carboxylicacid 97%
10g
$ 432.00

American Custom Chemicals Corporation
2-(4-METHOXYPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLIC ACID 95.00%
1G
$ 721.57

American Custom Chemicals Corporation
2-(4-METHOXYPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLIC ACID 95.00%
2.5G
$ 983.88

American Custom Chemicals Corporation
2-(4-METHOXYPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLIC ACID 95.00%
5G
$ 1168.42

Alfa Aesar
2-(4-Methoxyphenyl)-4-methylthiazole-5-carboxylic acid, 97%
1g
$ 74.40

Total 10 raw suppliers

Chemical Property of 2-(4-methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid

Chemical Property:

Vapor Pressure:4.85E-09mmHg at 25°C
Melting Point:236-241℃
Boiling Point:454.2°Cat760mmHg
Flash Point:228.5°C
PSA：87.66000
Density:1.31g/cm³
LogP:2.82530
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:249.04596439
Heavy Atom Count:17
Complexity:279

Purity/Quality:

98%+ ^*data from raw suppliers

2-(4-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(SC(=N1)C2=CC=C(C=C2)OC)C(=O)O

Technology Process of 2-(4-methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid

There total 3 articles about 2-(4-methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 54032-88-1
ethyl 4-methyl-2-[4-(methoxy)phenyl]-1,3-thiazole-5-carboxylate

: 54001-16-0
2-(4-methoxy phenyl)-4-methyl-1,3-thiazol-5-carboxylic acid

Guidance literature:: With sodium hydroxide; In ethanol; water; at 85 ℃; for 1.5h;
DOI:10.1021/jm058056x

Reference yield:

: 2362-64-3
p-methoxythiobenzamide

: 54001-16-0
2-(4-methoxy phenyl)-4-methyl-1,3-thiazol-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 24 h / Heating

2: 97 percent / NaOH / ethanol; H₂O / 1.5 h / 85 °C

With sodium hydroxide; In ethanol; water;
DOI:10.1021/jm058056x