2-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)ethanone

Base Information

• Chemical Name: 2-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)ethanone
• CAS No.: 94171-11-6
• Molecular Formula: C14H9Cl3O
• Molecular Weight: 299.584
• Hs Code.: 2914790090
• Mol file: 94171-11-6.mol

Synonyms:2-(4-chlorophenyl)-2',4'-dichloroacetophenone;2-(2-FLUOROPHENYL)OXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;4-chlorobenzyl 2,4-dichlorophenyl ketone;2-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-ethanone;Ethanone,2-(4-chlorophenyl)-1-(2,4-dichlorophenyl);

Chemical Property of 2-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)ethanone

Chemical Property:

• PSA: 17.07000
• LogP: 5.07220

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Chlorophenyl)-2',4'-dichloroacetophenone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)ethanone

There total 7 articles about 2-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-Chloro-4-(chloromethyl)benzene (104-83-6) + 2,4-dichlorobenzylnitrile (6574-98-7) → 2-(4-chlorophenyl)-1-(2,4-dichlorophenyl)ethanone (94171-11-6)

Guidance literature:

1-Chloro-4-(chloromethyl)benzene; With iodine; magnesium; In diethyl ether; for 1.5h; Heating;

2,4-dichlorobenzylnitrile; In toluene; at 135 ℃; for 2h;

With hydrogenchloride; water; In toluene;

DOI:10.1021/jm040843r

Reference yield: 79.0%

4-chlorophenylacetic Acid (1878-66-6) + methyl 2,4-dichlorobenzoate (35112-28-8) → 2-(4-chlorophenyl)-1-(2,4-dichlorophenyl)ethanone (94171-11-6)

Guidance literature:

4-chlorophenylacetic Acid; With sodium hexamethyldisilazane; In tetrahydrofuran; at -20 ℃;

methyl 2,4-dichlorobenzoate; In tetrahydrofuran;

DOI:10.1016/j.bmcl.2005.10.028

Reference yield: 39.0%

4-chlorophenacetyl chloride (25026-34-0) + 1,3-Dichlorobenzene (541-73-1) → 2-(4-chlorophenyl)-1-(2,4-dichlorophenyl)ethanone (94171-11-6)

Guidance literature:

With aluminium trichloride; at 0 - 20 ℃;

DOI:10.1016/j.bmc.2007.03.075

upstream raw materials:

1-Chloro-4-(chloromethyl)benzene

2,4-dichlorobenzylnitrile

4-chlorophenylacetic Acid

methyl 2,4-dichlorobenzoate

Downstream raw materials:

2-Chloro-2-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-ethanone

2-bromo-2-(4-chlorophenyl)-1-(2,4-dichlorophenyl)ethanone

3-chloro-2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)-acrylaldehyde

1-(4-chlorophenyl)-2-(2,4-dichlorophenyl)ethane-1,2-dione