Ethyl 1-benzyl-5-chloroindole-2-carboxylate

Base Information

Chemical Name:Ethyl 1-benzyl-5-chloroindole-2-carboxylate
CAS No.:95306-84-6
Molecular Formula:C18H16ClNO2
Molecular Weight:313.784
Hs Code.:
DSSTox Substance ID:DTXSID80535406
Wikidata:Q82409705

Synonyms:Ethyl 1-benzyl-5-chloroindole-2-carboxylate;95306-84-6;SCHEMBL1503984;DTXSID80535406;RIOJHKOPSLXMTN-UHFFFAOYSA-N;Ethyl 1-benzyl-5-chloro-1H-indole-2-carboxylate;1-benzyl-5-chloroindole-2-carboxylic acid ethyl ester;ethyl 5-chloro-1-(phenylmethyl)-1h-indole-2-carboxylate

Suppliers and Price of Ethyl 1-benzyl-5-chloroindole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Ethyl 1-benzyl-5-chloroindole-2-carboxylate

Chemical Property:

XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:313.0869564
Heavy Atom Count:22
Complexity:383

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC2=C(N1CC3=CC=CC=C3)C=CC(=C2)Cl

Technology Process of Ethyl 1-benzyl-5-chloroindole-2-carboxylate

There total 3 articles about Ethyl 1-benzyl-5-chloroindole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 4792-67-0
5-chloro-indole-2-carboxylic acid ethyl ester

: 100-44-7
benzyl chloride

: 95306-84-6
ethyl 1-benzyl-5-chloroindole-2-carboxylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 1.5h;
DOI:10.1016/j.bmc.2009.10.023

Reference yield:

: 100-39-0
benzyl bromide

: 95306-84-6
ethyl 1-benzyl-5-chloroindole-2-carboxylate

Guidance literature:: 5-chloro-indole-2-carboxylic acid ethyl ester; With sodium hydride; In N,N-dimethyl-formamide; for 0.333333h;

benzyl bromide; In N,N-dimethyl-formamide; for 2h;