1-benzyl-5-chloro-1H-indole-2-carboxylic acid

Base Information

Chemical Name:1-benzyl-5-chloro-1H-indole-2-carboxylic acid
CAS No.:1026645-16-8
Molecular Formula:C₁₆H₁₂ClNO₂
Molecular Weight:0
Hs Code.:
European Community (EC) Number:852-837-3
Mol file:1026645-16-8.mol

Synonyms:1-benzyl-5-chloro-1H-indole-2-carboxylic acid;1026645-16-8;1-benzyl-5-chloroindole-2-carboxylic acid;BRB64516;FT-0715351;EN300-12724382;Z3243016230

Suppliers and Price of 1-benzyl-5-chloro-1H-indole-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-benzyl-5-chloro-1H-indole-2-carboxylic acid

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:285.0556563
Heavy Atom Count:20
Complexity:356

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN2C3=C(C=C(C=C3)Cl)C=C2C(=O)O

Technology Process of 1-benzyl-5-chloro-1H-indole-2-carboxylic acid

There total 2 articles about 1-benzyl-5-chloro-1H-indole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: ethyl pyruvate N-benzyl-N-(4-chlorophenyl)hydrazone

: 1026645-16-8
5-chloro-1-benzylindole-2-carboxylic acid

Guidance literature:: With hydrogenchloride; In ethanol; for 2.5h; Heating;
DOI:10.1016/S0223-5234(99)80044-0

Reference yield:

: 95306-84-6
ethyl 1-benzyl-5-chloroindole-2-carboxylate

: 1026645-16-8
5-chloro-1-benzylindole-2-carboxylic acid

Guidance literature:: With water; potassium hydroxide; In ethanol;
DOI:10.1016/j.bmcl.2010.10.104

Reference yield:

: 4383-22-6
Allylbenzylamine

: 1026645-16-8
5-chloro-1-benzylindole-2-carboxylic acid

: N-allyl-N,1-dibenzyl-5-chloro-1H-indole-2-carboxamide

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 23 ℃;
DOI:10.1021/jacs.9b12129