Butanedioic acid, (1,3-benzodioxol-5-ylmethyl)-, 1-methyl ester

Base Information

• Chemical Name: Butanedioic acid, (1,3-benzodioxol-5-ylmethyl)-, 1-methyl ester
• CAS No.: 96548-65-1
• Molecular Formula: C₁₃H₁₄O₆
• Molecular Weight: 266.251
• Hs Code.: 2932999099
• Mol file: 96548-65-1.mol

Synonyms:BUTANEDIOICACID(1,3-BENZODIOXOL-5-YLMETHYL)-1-METHYLESTER;BUTANEDIOIC ACID(1,3-BENZODIOXOL-5-YLMETHYL)-1-METHYL ESTER;BUTANEDIOIC ACID, (1,3-BENZODIOXOL-5-YLMETHYL)-, 1-METHYL ESTER;

Chemical Property of Butanedioic acid, (1,3-benzodioxol-5-ylmethyl)-, 1-methyl ester

Chemical Property:

• Vapor Pressure: 4.12E-08mmHg at 25°C
• PSA: 82.06000
• LogP: 1.22170

Purity/Quality:

(1,3-BENZODIOXOL-5-YLMETHYL)BUTANEDIOIC ACID-1-METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Butanedioic acid, (1,3-benzodioxol-5-ylmethyl)-, 1-methyl ester

There total 9 articles about Butanedioic acid, (1,3-benzodioxol-5-ylmethyl)-, 1-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methyl hydrogen (E)-2-<3,4-(methylenedioxy)benzylidene>succinate (70381-89-4) → 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-methoxy-4-oxobutanoic acid (96548-65-1,68658-46-8)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethyl acetate;

Reference yield: 97.5%

(methylenedioxy-3,4 benzylidene) α-hemisuccinate de methyle (84736-28-7) → 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-methoxy-4-oxobutanoic acid (96548-65-1,68658-46-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In acetic acid; at 30 ℃; for 16h; under 22800 Torr;

DOI:10.1016/0040-4020(82)85093-X

Reference yield:

(E)-Dimethyl-2-((benzo[d][1,3]dioxol-6-yl)methylene) succinate → 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-methoxy-4-oxobutanoic acid (96548-65-1,68658-46-8)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 20 ℃; for 6h; under 760.051 Torr;

DOI:10.1021/acs.orglett.8b03670

upstream raw materials:

methyl hydrogen (E)-2-<3,4-(methylenedioxy)benzylidene>succinate

(S)-(-)-α-(methylenedioxy-3,4 benzyl)hemisuccinate de methyle

(methylenedioxy-3,4 benzylidene) α-hemisuccinate de methyle

piperonal

Downstream raw materials:

4-Benzo[1,3]dioxol-5-ylmethyl-3-[hydroxy-(3,4,5-trimethoxy-phenyl)-methyl]-dihydro-furan-2-one

(E)-3-(3,4,5-trimethoxybenzylidene)-4-((benzo-[d][1,3]dioxol-5-yl)methyl)dihydrofuran-2(3H)-one