2-amino-5-oxo-4-phenyl-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile

Base Information

• Chemical Name: 2-amino-5-oxo-4-phenyl-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile
• CAS No.: 96767-93-0
• Molecular Formula: C19H12N2O3
• Molecular Weight: 316.316
• Mol file: 96767-93-0.mol

Synonyms:2-amino-4,5-dihydro-4-(phenyl)-5-oxopyrano[3,2-c]chromene-3-carbonitrile;2-amino-4,5-dihydro-5-oxo-4-phenylpyrano[3,2-c]chromene-3-carbonitrile;2‐amino‐4,5‐dihydro‐4‐(phenyl)‐5‐oxopyrano[3,2‐c]chromene‐3‐carbonitrile;2-Amino-5-oxo-4-phenyl-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile;2-amino-4-phenyl-5-oxo-4H,5H-pyrano-[3,2-c]chromene-3-carbonitrile;2-amino-5-oxo-4-phenyl-3-cyano-4H-pyrano<3,2-c><1>-benzopyran;2-amino-4,5-dihydro-4-phenyl-5-oxo-pyrano[3,2-c]chromene-3-carbonitrile;

Chemical Property of 2-amino-5-oxo-4-phenyl-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile

Chemical Property:

• PSA: 89.25000
• LogP: 3.71148

Purity/Quality:

2-AMINO-5-OXO-4-PHENYL-4H,5H-PYRANO(3,2-C)CHROMENE-3-CARBONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-amino-5-oxo-4-phenyl-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile

There total 12 articles about 2-amino-5-oxo-4-phenyl-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-hydroxy[1]benzopyran-2-one (1076-38-6,92395-12-5) + benzaldehyde (100-52-7) + malononitrile (109-77-3) → 2-amino-5-oxo-4-phenyl-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile (96767-93-0)

Guidance literature:

benzaldehyde; malononitrile; With polyethyleneimine covalently bound on the surface of of Fe₃O₄ magnetic nanoparticle by [3-(2,3-epoxypropoxy)propyl]trimethoxysilane as cross linker; In water; for 0.0166667h; Sonication; Green chemistry;

4-hydroxy[1]benzopyran-2-one; In water; for 1h; Reagent/catalyst; Temperature; Time; Solvent; Sonication; Green chemistry;

DOI:10.1016/j.jmmm.2014.09.044

Reference yield: 98.0%

4-hydroxy-3-(phenyl(pyrrolidin-1-yl)methyl)-2H-chromen-2-one (1330776-87-8) + malononitrile (109-77-3) → 2-amino-5-oxo-4-phenyl-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile (96767-93-0)

Guidance literature:

In acetonitrile; at 50 ℃; for 0.75h;

DOI:10.1039/c5ra22440c

Reference yield: 95.0%

4‐hydroxycoumarin (22105-09-5) + benzaldehyde (100-52-7) + malononitrile (109-77-3) → 2-amino-5-oxo-4-phenyl-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile (96767-93-0)

Guidance literature:

With bifunctional periodic mesoporous organosilica supported isatin-Schiff-base/manganese(II) complex nanocatalyst; In ethanol; water; at 20 ℃; for 0.25h; Reagent/catalyst; Solvent; Catalytic behavior;

DOI:10.1007/s10562-019-02653-6

upstream raw materials:

4-hydroxy[1]benzopyran-2-one

Benzylidenemalononitrile

benzaldehyde

malononitrile

Downstream raw materials:

8-amino-7-phenyl-9,10,11,12-tetrahydrochromeno[3',4':5,6]pyrano[2,3-b]quinolin-6(7H)-one