Phosphonium, bis(hydroxymethyl)diphenyl-, chloride

Base Information

• Chemical Name: Phosphonium, bis(hydroxymethyl)diphenyl-, chloride
• CAS No.: 96776-80-6
• Molecular Formula: C14H16O2P.Cl
• Molecular Weight: 282.707
• DSSTox Substance ID: DTXSID30382725
• Mol file: 96776-80-6.mol

Synonyms:Phosphonium, bis(hydroxymethyl)diphenyl-, chloride;96776-80-6;SCHEMBL7774175;DTXSID30382725;AKOS004908944

Chemical Property of Phosphonium, bis(hydroxymethyl)diphenyl-, chloride

Chemical Property:

• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 282.0576444
• Heavy Atom Count: 18
• Complexity: 196

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)[P+](CO)(CO)C2=CC=CC=C2.[Cl-]

Technology Process of Phosphonium, bis(hydroxymethyl)diphenyl-, chloride

There total 3 articles about Phosphonium, bis(hydroxymethyl)diphenyl-, chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + diphenylphosphane (829-85-6) → diphenyl-bis(hydroxymethyl)phosphonium chloride (96776-80-6)

Guidance literature:

With hydrogenchloride; In water; Inert atmosphere;

DOI:10.1039/c1nj20375d

Reference yield: 89.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + triphenylphosphine (603-35-0) → diphenyl-bis(hydroxymethyl)phosphonium chloride (96776-80-6)

Guidance literature:

triphenylphosphine; With lithium; In water; Inert atmosphere;

formaldehyd; With hydrogenchloride; In tetrahydrofuran; Inert atmosphere;

DOI:10.1007/s10562-013-1028-0

Reference yield:

N,N-dimethyl-formamide (68-12-2,33513-42-7) + diphenylphosphane (829-85-6) → diphenyl-bis(hydroxymethyl)phosphonium chloride (96776-80-6)

Guidance literature:

With hydrogenchloride; In water;

DOI:10.1016/j.jorganchem.2020.121650

upstream raw materials:

formaldehyd

diphenylphosphane

triphenylphosphine

N,N-dimethyl-formamide

Downstream raw materials:

Bis-chlormethyl-diphenyl-phosphoniumchlorid

diphenylphosphinomethanol

[N,N-bis(diphenylphospinomethyl)aminomethane]

(Ph₂PCH₂)2N-m-C₆H₄SO₃Na