Ethanone, 1-[4-[(4-methoxyphenyl)thio]phenyl]-

Base Information

• Chemical Name: Ethanone, 1-[4-[(4-methoxyphenyl)thio]phenyl]-
• CAS No.: 97361-14-3
• Molecular Formula: C15H14O2S
• Molecular Weight: 258.341
• Mol file: 97361-14-3.mol

Synonyms:

Chemical Property of Ethanone, 1-[4-[(4-methoxyphenyl)thio]phenyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethanone, 1-[4-[(4-methoxyphenyl)thio]phenyl]-

There total 13 articles about Ethanone, 1-[4-[(4-methoxyphenyl)thio]phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-Methoxybenzenethiol (696-63-9) + 4-Iodoacetophenone (13329-40-3) → 1-(4-((4-methoxyphenyl)thio)phenyl)ethan-1-one (97361-14-3)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; copper(l) iodide; potassium carbonate; In 1,2-dimethoxyethane; at 120 ℃; for 12h; chemoselective reaction; Sealed tube; Inert atmosphere;

DOI:10.1016/j.tetlet.2015.10.014

Reference yield: 91.0%

4,4'-dimethoxyphenyl disulfide (5335-87-5) + 1-(4-fluorophenyl)ethanone (403-42-9) → 1-(4-((4-methoxyphenyl)thio)phenyl)ethan-1-one (97361-14-3)

Guidance literature:

With hydridotetakis(triphenylphosphine)rhodium(I); o-phenylenebis(diphenylphosphine); triphenylphosphine; In chlorobenzene; for 6h; Reflux;

DOI:10.1021/ja8049996

Reference yield: 87.0%

4,4'-dimethoxyphenyl disulfide (5335-87-5) + 1-(4-acetylphenyl)diazonium tetrafluoroborate (350-47-0) → 1-(4-((4-methoxyphenyl)thio)phenyl)ethan-1-one (97361-14-3)

Guidance literature:

With zinc; In carbonic acid dimethyl ester; at 80 ℃; for 0.416667h; Microwave irradiation;

DOI:10.1039/c2gc35328h

upstream raw materials:

4-Methoxybenzenethiol

4-Iodoacetophenone

4,4'-dimethoxyphenyl disulfide

1-(4-fluorophenyl)ethanone

Refernces

• 1、 Ball, Liam T.,Maggi, Lorenzo,Park, Mahri,Shepherd, William,Swan, Charlie,Taylor, Sophie. "Generation of Thiyl Radicals from Air-Stable, Odorless Thiophenol Surrogates: Application to Visible-Light-Promoted C-S Cross-Coupling". . . Retrieved 2022/02/25.
• 2、 Thomas, Anns Maria,Sherin,Asha, Sujatha,Manojkumar,Anilkumar, Gopinathan. "Exploration of the mechanism and scope of the CuI/DABCO catalysed C–S coupling reaction". supporting information. . Retrieved 2019/12/26.