4-Methoxy-N-methyl-N-nitrosobenzamide

Base Information

• Chemical Name: 4-Methoxy-N-methyl-N-nitrosobenzamide
• CAS No.: 97661-70-6
• Molecular Formula: C9H10N2O3
• Molecular Weight: 194.19
• DSSTox Substance ID: DTXSID40541508
• Nikkaji Number: J450.210H
• Wikidata: Q82417880
• Mol file: 97661-70-6.mol

Synonyms:4-Methoxy-N-methyl-N-nitrosobenzamide;97661-70-6;DTXSID40541508

Chemical Property of 4-Methoxy-N-methyl-N-nitrosobenzamide

Chemical Property:

• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 194.06914219
• Heavy Atom Count: 14
• Complexity: 212

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN(C(=O)C1=CC=C(C=C1)OC)N=O

Technology Process of 4-Methoxy-N-methyl-N-nitrosobenzamide

There total 1 articles about 4-Methoxy-N-methyl-N-nitrosobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-methyl-p-anisylimidoyl chloride (78554-86-6) → C9H10N2O4 (97661-72-8) + 4-methoxy-N-methyl-N-nitrosobenzamide (97661-70-6)

Guidance literature:

With silver nitrate; In acetonitrile; at -30 ℃; for 0.5h;

Reference yield: 75.0%

4-methoxy-N-methyl-N-nitrosobenzamide (97661-70-6) + 2-(trimethylsilyl)phenyl trifluoromethanesulfonate (88284-48-4) → (1H-indazol-1-yl)(4-methoxyphenyl)methanone

Guidance literature:

With potassium fluoride; 18-crown-6 ether; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1039/d1cc05655g

Reference yield:

4-methoxy-N-methyl-N-nitrosobenzamide (97661-70-6) + benzylamine (100-46-9) → N-benzyl-4-methoxybenzamide (7465-87-4)

Guidance literature:

In dichloromethane; at 25 - 27 ℃; for 3h;

DOI:10.1039/c8ob03010c

upstream raw materials:

N-methyl-p-anisylimidoyl chloride

Downstream raw materials:

N-benzyl-4-methoxybenzamide

N-butyl-p-methoxybenzamide

N-cyclohexyl-4-methoxybenzamide

4-methoxy-N-(1-methylethyl)benzamide

Refernces