(S)-2-AMINOHEX-5-YNOIC ACID

Base Information

Chemical Name:(S)-2-AMINOHEX-5-YNOIC ACID
CAS No.:98891-36-2
Molecular Formula:C6H9NO2
Molecular Weight:127.143
Hs Code.:2922499990
Mol file:98891-36-2.mol

Synonyms:homoproparglyglycine;L-homopropargylglycine;

Suppliers and Price of (S)-2-AMINOHEX-5-YNOIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
L-Homopropargylglycine
5mg
$ 355.00

TRC
L-Homopropargylglycine
2.5mg
$ 385.00

SynQuest Laboratories
L-Homopropargylglycine
1 g
$ 1495.00

SynQuest Laboratories
L-Homopropargylglycine
200 mg
$ 495.00

SynQuest Laboratories
L-Homopropargylglycine
500 mg
$ 995.00

chempep
H-HomoGly(Propargyl)-OH >=98%
1g
$ 1096.00

Chem-Impex
L-Homopropargylglycine (HPG) ≥ 95%
1G
$ 1250.00

Chem-Impex
L-Homopropargylglycine (HPG) ≥ 95%
100MG
$ 260.00

Chem-Impex
L-Homopropargylglycine(HPG),95% 95%
25MG
$ 145.60

Chem-Impex
L-Homopropargylglycine (HPG) ≥ 95%
5MG
$ 70.00

Total 10 raw suppliers

Chemical Property of (S)-2-AMINOHEX-5-YNOIC ACID

Chemical Property:

Melting Point:162°C
PSA：63.32000
LogP:0.51200
Storage Temp.:-20°C
Solubility.:Aqueous Acid (Sparingly), Methanol (Slightly), Water (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

L-Homopropargylglycine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses L-Homopropargyl glycine is a reactive methionine analog that contains an alkyne moiety. It is readily inserted into newly-synthesized proteins in place of methionine. L-Homopropargyl glycine can then be labeled or captured through click chemistry. This approach represents a fast, sensitive, and non-radioactive alternative to [35S]-methionine for the detection of nascent protein synthesis. L-Homopropargylglycine (HPG) is an amino acid analog of methionine that contains a very small modification, specifically an alkyne moiety. (S)-2-AMINOHEX-5-YNOIC ACID can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click” reaction between an azide and an alkyne or cyclooctyne. For example the alkyne-modified protein can be detected with either fluorescent azide or biotin azide. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.

Technology Process of (S)-2-AMINOHEX-5-YNOIC ACID

There total 6 articles about (S)-2-AMINOHEX-5-YNOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 38771-21-0
4-bromobut-1-yne

: 98891-36-2
(S)-2-amino-5-hexynoic acid

Guidance literature:: 4-bromobut-1-yne; Ni(II) complex of the Schiff base derived from glycine and (S)-2-[N'-(N-benzylprolyl)amino]benzophenone; With sodium hydroxide; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;

With hydrogenchloride; water; In methanol; for 1h; Further stages.; Heating;
DOI:10.1039/a908140b

Reference yield: 40.0%

: 2-amino-5-hexynoic acid amide hydrochloride

: 98891-36-2
(S)-2-amino-5-hexynoic acid

: 767279-09-4
(R)-2-amino-5-hexynoic acid amide

Guidance literature:: With potassium hydroxide; manganese(II) sulfate; E. coli DH5α; pTrpLAP GMO whole cells (S-aminopeptidase); In water; at 40 ℃; for 21h; pH=9.2; Enzymatic reaction;
DOI:10.1002/1615-4169(200108)343:6/7<662::aid-adsc662>3.3.co;2-9