(R)-2-amino-5-hexynoic acid amide

Base Information

• Chemical Name: (R)-2-amino-5-hexynoic acid amide
• CAS No.: 767279-09-4
• Molecular Formula: C₆H₁₀N₂O
• Molecular Weight: 126.158
• Mol file: 767279-09-4.mol

Synonyms:

Chemical Property of (R)-2-amino-5-hexynoic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-2-amino-5-hexynoic acid amide

There total 1 articles about (R)-2-amino-5-hexynoic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

2-amino-5-hexynoic acid amide hydrochloride → (S)-2-amino-5-hexynoic acid (98891-36-2) + (R)-2-amino-5-hexynoic acid amide (767279-09-4)

Guidance literature:

With potassium hydroxide; manganese(II) sulfate; E. coli DH5α; pTrpLAP GMO whole cells (S-aminopeptidase); In water; at 40 ℃; for 21h; pH=9.2; Enzymatic reaction;

DOI:10.1002/1615-4169(200108)343:6/7<662::aid-adsc662>3.3.co;2-9

Reference yield: 99.0%

(R)-2-amino-5-hexynoic acid amide (767279-09-4) → (R)-2-amino-5-hexynoic acid (211054-02-3)

Guidance literature:

With Rhodococcus erythropolis NCIMB 11540 (whole cells, amidase); In phosphate buffer; at 37 ℃; for 3h; pH=8; Enzymatic reaction;

DOI:10.1002/1615-4169(200108)343:6/7<662::aid-adsc662>3.3.co;2-9

Reference yield:

benzaldehyde (100-52-7) + (R)-2-amino-5-hexynoic acid amide (767279-09-4) → (R)-2-{[1-Phenyl-meth-(E)-ylidene]-amino}-hex-5-ynoic acid amide

Guidance literature:

With sodium hydroxide; at 20 ℃; for 2h; pH=8 - 9;

DOI:10.1002/1615-4169(200108)343:6/7<662::aid-adsc662>3.3.co;2-9

Downstream raw materials:

(R)-2-amino-5-hexynoic acid