2,5-Pyrrolidinedione, 1-[(4-azido-2-hydroxy-5-iodobenzoyl)oxy]-

Base Information

Chemical Name:2,5-Pyrrolidinedione, 1-[(4-azido-2-hydroxy-5-iodobenzoyl)oxy]-
CAS No.:99298-06-3
Molecular Formula:C11H7IN4O5
Molecular Weight:402.105
Hs Code.:
DSSTox Substance ID:DTXSID00468489
Wikidata:Q82295700

Synonyms:2,5-Pyrrolidinedione, 1-[(4-azido-2-hydroxy-5-iodobenzoyl)oxy]-;99298-06-3;DTXSID00468489

Suppliers and Price of 2,5-Pyrrolidinedione, 1-[(4-azido-2-hydroxy-5-iodobenzoyl)oxy]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,5-Pyrrolidinedione, 1-[(4-azido-2-hydroxy-5-iodobenzoyl)oxy]-

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:401.94612
Heavy Atom Count:21
Complexity:505

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1=O)OC(=O)C2=CC(=C(C=C2O)N=[N+]=[N-])I

Technology Process of 2,5-Pyrrolidinedione, 1-[(4-azido-2-hydroxy-5-iodobenzoyl)oxy]-

There total 5 articles about 2,5-Pyrrolidinedione, 1-[(4-azido-2-hydroxy-5-iodobenzoyl)oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 96602-46-9
succinimide 4-azidosalicylate

: 99298-06-3
4-azido-2-hydroxy-5-iodobenzoic acid N-hydroxysuccinimide ester

Guidance literature:: With chloroamine-T; sodium iodide; In acetonitrile; at 25 ℃; for 1h;
DOI:10.1016/S0040-4039(00)94774-9

Reference yield:

: 66761-27-1
4-carboxy-3-hydroxyphenyl azide

: 99298-06-3
4-azido-2-hydroxy-5-iodobenzoic acid N-hydroxysuccinimide ester

Guidance literature:: Multi-step reaction with 2 steps

1: 42 percent / 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride / CH₂Cl₂; dimethylformamide / 20 °C

2: 11 percent / NaI; chloramine T / acetonitrile / 1 h / 20 °C

With chloroamine-T; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium iodide; In dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm050644n

Reference yield:

: 87877-90-5
methyl 4-azido-2-hydroxybenzoate

: 99298-06-3
4-azido-2-hydroxy-5-iodobenzoic acid N-hydroxysuccinimide ester

Guidance literature:: Multi-step reaction with 3 steps

1: chloramine T, sodium iodide / dimethylformamide

2: sodium hydroxide / ethanol / 3 h / Heating

3: pyridine / acetonitrile / 16 h / Ambient temperature

With pyridine; sodium hydroxide; chloroamine-T; sodium iodide; In ethanol; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/0223-5234(90)90121-I