(R)-2-HYDROXYMETHYL-PIPERAZINE-2HCl

Base Information

Chemical Name:(R)-2-HYDROXYMETHYL-PIPERAZINE-2HCl
CAS No.:149715-47-9
Molecular Formula:C5H12N2O
Molecular Weight:116.163
Hs Code.:
Mol file:149715-47-9.mol

Synonyms:(R)-2-HYDROXYMETHYL-PIPERAZINE-2HCl;(R)-Piperazin-2-ylMethanol dihydrochloride;(R)-Piperazin-2-ylMethanol 2HCl;(R)-2-Piperazinemethanol;(R)-Piperazin-2-ylMethanol

Suppliers and Price of (R)-2-HYDROXYMETHYL-PIPERAZINE-2HCl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-2-Hydroxymethyl-piperazine
10mg
$ 45.00

TRC
(R)-2-Hydroxymethyl-piperazine
100mg
$ 285.00

J&W Pharmlab
(R)-Piperazin-2-yl-methanol 97%
5g
$ 3998.00

Crysdot
(R)-Piperazin-2-ylmethanol 95+%
1g
$ 290.00

Chemenu
(R)-piperazin-2-ylmethanol 95%
1g
$ 271.00

American Custom Chemicals Corporation
(2R)-2-PIPERAZINEMETHANOL 95.00%
1G
$ 1050.00

American Custom Chemicals Corporation
(2R)-2-PIPERAZINEMETHANOL 95.00%
5MG
$ 503.00

Ambeed
(R)-Piperazin-2-ylmethanol 95+%
100mg
$ 39.00

Ambeed
(R)-Piperazin-2-ylmethanol 95+%
1g
$ 147.00

Ambeed
(R)-Piperazin-2-ylmethanol 95+%
250mg
$ 62.00

Total 22 raw suppliers

Chemical Property of (R)-2-HYDROXYMETHYL-PIPERAZINE-2HCl

Chemical Property:

Boiling Point:234.5±20.0 °C(Predicted)
PKA:14.97±0.10(Predicted)
PSA：44.29000
Density:0.992±0.06 g/cm3(Predicted)
LogP:-0.80230
Storage Temp.:2-8°C(protect from light)

Purity/Quality:

98% ^*data from raw suppliers

(R)-2-Hydroxymethyl-piperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-2-HYDROXYMETHYL-PIPERAZINE-2HCl

There total 3 articles about (R)-2-HYDROXYMETHYL-PIPERAZINE-2HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 149715-46-8
(R)-4-(phenylmethyl)-2-piperazinemethanol

: 149715-47-9
(R)-piperazin-2-ylmethanol

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 760 Torr;
DOI:10.1021/jm00067a004

Reference yield:

: 149648-97-5
(S)-3-(hydroxymethyl)-1-(phenylmethyl)-2,5-piperazinedione

: 149715-47-9
(R)-piperazin-2-ylmethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / LiAlH₄ / tetrahydrofuran / 1.5 h / Heating

2: 56 percent / H₂ / 5percent Pd/C / ethanol / 760 Torr

With lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00067a004

Reference yield:

: 149648-96-4
N-<(1,1-dimethylethoxy)carbonyl>-N-(phenylmethyl)glycyl-L-serine methyl ester

: 149715-47-9
(R)-piperazin-2-ylmethanol

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) SOCl₂, 2.) aq. NH₃ / 1.) methanol, RT, 2 h, 2.) methanol

2: 91 percent / LiAlH₄ / tetrahydrofuran / 1.5 h / Heating

3: 56 percent / H₂ / 5percent Pd/C / ethanol / 760 Torr

With ammonium hydroxide; lithium aluminium tetrahydride; thionyl chloride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00067a004