1-Piperazinecarboxylicacid,3-(hydroxymethyl)-,methylester,(R)-(9CI)

Base Information

Chemical Name:1-Piperazinecarboxylicacid,3-(hydroxymethyl)-,methylester,(R)-(9CI)
CAS No.:149648-98-6
Molecular Formula:C₇H₁₄N₂O₃
Molecular Weight:174.2
Hs Code.:
Mol file:149648-98-6.mol

Synonyms:1-Piperazinecarboxylicacid,3-(hydroxymethyl)-,methylester,(R)-(9CI);METHYL (3R)-3-(HYDROXYMETHYL)PIPERAZINE-1-CARBOXYLATE

Suppliers and Price of 1-Piperazinecarboxylicacid,3-(hydroxymethyl)-,methylester,(R)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Piperazinecarboxylicacid,3-(hydroxymethyl)-,methylester,(R)-(9CI)

Chemical Property:

PSA：61.80000
LogP:-0.71440

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Piperazinecarboxylicacid,3-(hydroxymethyl)-,methylester,(R)-(9CI)

There total 4 articles about 1-Piperazinecarboxylicacid,3-(hydroxymethyl)-,methylester,(R)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 79-22-1
methyl chloroformate

: 149715-47-9
(R)-piperazin-2-ylmethanol

: 149648-98-6
(R)-methyl 3-(hydroxymethyl)-1-piperazinecarboxylate

Guidance literature:: In acetonitrile; for 0.5h; Ambient temperature;
DOI:10.1021/jm00067a004

Reference yield:

: 149715-46-8
(R)-4-(phenylmethyl)-2-piperazinemethanol

: 149648-98-6
(R)-methyl 3-(hydroxymethyl)-1-piperazinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 56 percent / H₂ / 5percent Pd/C / ethanol / 760 Torr

2: 96 percent / acetonitrile / 0.5 h / Ambient temperature

With hydrogen; palladium on activated charcoal; In ethanol; acetonitrile;
DOI:10.1021/jm00067a004

Reference yield:

: 149648-97-5
(S)-3-(hydroxymethyl)-1-(phenylmethyl)-2,5-piperazinedione

: 149648-98-6
(R)-methyl 3-(hydroxymethyl)-1-piperazinecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / LiAlH₄ / tetrahydrofuran / 1.5 h / Heating

2: 56 percent / H₂ / 5percent Pd/C / ethanol / 760 Torr

3: 96 percent / acetonitrile / 0.5 h / Ambient temperature

With lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetonitrile;
DOI:10.1021/jm00067a004