N-(6-methyl-4-oxo-1,4-dihydropyrimidin-5-yl)acetamide

Base Information

Chemical Name:N-(6-methyl-4-oxo-1,4-dihydropyrimidin-5-yl)acetamide
CAS No.:6965-60-2
Molecular Formula:C₇H₉N₃O₂
Molecular Weight:167.167
Hs Code.:

Synonyms:Acetamide,N-(1,4-dihydro-6-methyl-4-oxo-5-pyrimidinyl)- (9CI); Acetamide,N-(4-hydroxy-6-methyl-5-pyrimidinyl)- (8CI); NSC 69211

Suppliers and Price of N-(6-methyl-4-oxo-1,4-dihydropyrimidin-5-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of N-(6-methyl-4-oxo-1,4-dihydropyrimidin-5-yl)acetamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.35g/cm³

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-(6-methyl-4-oxo-1,4-dihydropyrimidin-5-yl)acetamide

There total 2 articles about N-(6-methyl-4-oxo-1,4-dihydropyrimidin-5-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 6965-56-6
5-Acetylamino-6-methyl-4-oxo-2-thio-1,2,3,4-tetrahydropyrimidine

: 6965-60-2
5-Acetylamino-6-methyl-4-oxo-3,4-dihydropyrimidine

Guidance literature:: With ammonium hydroxide; nickel; In water; at 80 ℃; for 2h;
DOI:10.1007/BF00773110

Reference yield:

: 5431-93-6
ethyl 2-(acetylamino)-3-oxobutanoate

: 6965-60-2
5-Acetylamino-6-methyl-4-oxo-3,4-dihydropyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / 24percent aq. NaOH / 4 h / 60 - 70 °C

2: 72 percent / 25percent aq. NH₃, Raney nickel / H₂O / 2 h / 80 °C

With ammonium hydroxide; sodium hydroxide; nickel; In water;
DOI:10.1007/BF00773110

Reference yield:

: 6965-60-2
5-Acetylamino-6-methyl-4-oxo-3,4-dihydropyrimidine

: 75682-10-9
4-Oxo-3,4-dihydropyrrolo<3,2-d>pyrimidine-7-carboxaldehyde phenylhydrazone

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / conc. aq. HCl / 5 h / Heating

2: phosphorus oxychloride / dimethylformamide / 1 h / 80 °C

3: NaHCO₃ / H₂O

4: dimethylformamide / 1 h / 100 °C

With hydrogenchloride; sodium hydrogencarbonate; trichlorophosphate; In water; N,N-dimethyl-formamide;
DOI:10.1007/BF00773110