N-(6-methyl-4-oxo-2-sulfanylidene-1H-pyrimidin-5-yl)acetamide

Base Information

Chemical Name:N-(6-methyl-4-oxo-2-sulfanylidene-1H-pyrimidin-5-yl)acetamide
CAS No.:6965-56-6
Molecular Formula:C₇H₉N₃O₂S
Molecular Weight:199.233
Hs Code.:
NSC Number:69207
DSSTox Substance ID:DTXSID30391296

Synonyms:NSC69207;6965-56-6;NCIOpen2_000333;DTXSID30391296;NSC-69207

Suppliers and Price of N-(6-methyl-4-oxo-2-sulfanylidene-1H-pyrimidin-5-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of N-(6-methyl-4-oxo-2-sulfanylidene-1H-pyrimidin-5-yl)acetamide

Chemical Property:

Density:1.4g/cm³
XLogP3:-0.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:199.04154771
Heavy Atom Count:13
Complexity:322

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)NC(=S)N1)NC(=O)C

Technology Process of N-(6-methyl-4-oxo-2-sulfanylidene-1H-pyrimidin-5-yl)acetamide

There total 1 articles about N-(6-methyl-4-oxo-2-sulfanylidene-1H-pyrimidin-5-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 5431-93-6
ethyl 2-(acetylamino)-3-oxobutanoate

: 17356-08-0
thiourea

: 6965-56-6
5-Acetylamino-6-methyl-4-oxo-2-thio-1,2,3,4-tetrahydropyrimidine

Guidance literature:: With sodium hydroxide; at 60 - 70 ℃; for 4h;
DOI:10.1007/BF00773110

Reference yield: 72.0%

: 6965-56-6
5-Acetylamino-6-methyl-4-oxo-2-thio-1,2,3,4-tetrahydropyrimidine

: 6965-60-2
5-Acetylamino-6-methyl-4-oxo-3,4-dihydropyrimidine

Guidance literature:: With ammonium hydroxide; nickel; In water; at 80 ℃; for 2h;
DOI:10.1007/BF00773110

Reference yield:

: 6965-56-6
5-Acetylamino-6-methyl-4-oxo-2-thio-1,2,3,4-tetrahydropyrimidine

: 75682-10-9
4-Oxo-3,4-dihydropyrrolo<3,2-d>pyrimidine-7-carboxaldehyde phenylhydrazone

Guidance literature:: Multi-step reaction with 5 steps

1: 72 percent / 25percent aq. NH₃, Raney nickel / H₂O / 2 h / 80 °C

2: 75 percent / conc. aq. HCl / 5 h / Heating

3: phosphorus oxychloride / dimethylformamide / 1 h / 80 °C

4: NaHCO₃ / H₂O

5: dimethylformamide / 1 h / 100 °C

With hydrogenchloride; ammonium hydroxide; nickel; sodium hydrogencarbonate; trichlorophosphate; In water; N,N-dimethyl-formamide;
DOI:10.1007/BF00773110