N~1~-(7-Chloroquinolin-4-yl)-N~4~-(propan-2-yl)cyclohexane-1,4-diamine

Base Information

Chemical Name:N~1~-(7-Chloroquinolin-4-yl)-N~4~-(propan-2-yl)cyclohexane-1,4-diamine
CAS No.:6633-00-7
Molecular Formula:C18H24ClN3
Molecular Weight:317.862
Hs Code.:
NSC Number:56625
DSSTox Substance ID:DTXSID70984924
ChEMBL ID:CHEMBL258590

Synonyms:MLS002667835;6633-00-7;NSC56625;NCIOpen2_007494;CHEMBL258590;SCHEMBL1147688;DTXSID70984924;HMS3079E04;NSC-56625;SMR001557592;N~1~-(7-Chloroquinolin-4-yl)-N~4~-(propan-2-yl)cyclohexane-1,4-diamine

Suppliers and Price of N~1~-(7-Chloroquinolin-4-yl)-N~4~-(propan-2-yl)cyclohexane-1,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of N~1~-(7-Chloroquinolin-4-yl)-N~4~-(propan-2-yl)cyclohexane-1,4-diamine

Chemical Property:

Boiling Point:473.1°Cat760mmHg
Flash Point:239.9°C
Density:1.16g/cm³
XLogP3:4.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:317.1658755
Heavy Atom Count:22
Complexity:341

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)NC1CCC(CC1)NC2=C3C=CC(=CC3=NC=C2)Cl

Technology Process of N~1~-(7-Chloroquinolin-4-yl)-N~4~-(propan-2-yl)cyclohexane-1,4-diamine

There total 2 articles about N~1~-(7-Chloroquinolin-4-yl)-N~4~-(propan-2-yl)cyclohexane-1,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 289628-25-7
cis-N-(7-chloro-quinolin-4-yl)-cyclohexyl-1,4-diamine

: 67-64-1
acetone

: 6633-00-7
N-(7-chloro-4-quinolyl)-N'-isopropyl-1,4-diaminocyclohexane

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jm800106u

Reference yield:

: 86-98-6,1138471-54-1
4,7-dichloroquinoline

: 6633-00-7
N-(7-chloro-4-quinolyl)-N'-isopropyl-1,4-diaminocyclohexane

Guidance literature:: Multi-step reaction with 2 steps

1.1: 18 h / 110 °C / Inert atmosphere

1.2: 20 °C

2.1: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 2 h / 20 °C

With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane;