Pyrazinecarbohydroxamic acid

Base Information

• Chemical Name: Pyrazinecarbohydroxamic acid
• CAS No.: 768-06-9
• Molecular Formula: C5H5N3O2
• Molecular Weight: 139.1121
• NSC Number: 132088
• UNII: X7ZW8Y55ZE
• DSSTox Substance ID: DTXSID50998120
• Nikkaji Number: J2.633.363F
• Wikidata: Q82990623
• Mol file: 768-06-9.mol

Synonyms:Pyrazinecarbohydroxamic acid;768-06-9;N-Hydroxypyrazine-2-carboxamide;NSC-132088;NSC22944;6949-85-5;2-Pyrazinecarboxamide, N-hydroxy-;Pyrazinehydroxamic acid;Pyrazinohydroxamic acid;X7ZW8Y55ZE;pyrazine-2-carbohydroxamic acid;SCHEMBL1412848;N-Hydroxy-2-pyrazinecarboxamide;Pyrazinecarboxamide, N-hydroxy-;SCHEMBL18530687;DTXSID50998120;NSC132088;N-Hydroxypyrazine-2-carboximidic acid;N-Hydroxy-2-pyrazinecarboxamide (ACI);Pyrazine-2-carboxylic acid hydroxyamide;EN300-1294301

Chemical Property of Pyrazinecarbohydroxamic acid

Chemical Property:

• Vapor Pressure: 0.0428mmHg at 25°C
• Boiling Point: 238.3°Cat760mmHg
• Flash Point: 97.9°C
• Density: 1.49g/cm³
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 139.038176411
• Heavy Atom Count: 10
• Complexity: 128

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CN=C(C=N1)C(=O)NO

Technology Process of Pyrazinecarbohydroxamic acid

There total 2 articles about Pyrazinecarbohydroxamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl pyrazine-2-carboxylate (6164-79-0) → pyrazinehydroxamic acid (768-06-9)

Guidance literature:

With hydroxylamine; In methanol; at 20 ℃; for 72h;

DOI:10.1007/s00775-020-01805-z

Reference yield:

→ pyrazinehydroxamic acid (768-06-9)

Guidance literature:

Pyrazin-2-carbonsaeure-methylester (III), Hydroxylamin;

Reference yield: 69.0%

pyrazinehydroxamic acid (768-06-9) + methylamine (74-89-5) → N-methylpyrazine-2-carboxamide (88393-94-6)

Guidance literature:

With potassium hexacyanoferrate(III); In aq. phosphate buffer; at 20 ℃; for 2h; pH=7.4;

DOI:10.1039/d0nj00753f

upstream raw materials:

methyl pyrazine-2-carboxylate

Downstream raw materials:

N-methylpyrazine-2-carboxamide

Refernces