3-(2-hydroxyethyl)-2-mercaptoquinazolin-4(3H)-one

Base Information

Chemical Name:3-(2-hydroxyethyl)-2-mercaptoquinazolin-4(3H)-one
CAS No.:16024-85-4
Molecular Formula:C₁₀H₁₀N₂O₂S
Molecular Weight:222.268
Hs Code.:2933990090
European Community (EC) Number:869-155-7
DSSTox Substance ID:DTXSID60350139
Wikidata:Q82125923
Mol file:16024-85-4.mol

Synonyms:16024-85-4;3-(2-hydroxyethyl)-2-mercaptoquinazolin-4(3H)-one;3-(2-hydroxyethyl)-2-sulfanylidene-1H-quinazolin-4-one;3-(2-hydroxyethyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one;3-(2-hydroxyethyl)-2-thioxo-1,3-dihydroquinazolin-4-one;DTXSID60350139;HMS1592A01;AKOS001060476;AKOS005198753;CS-0221213;EN300-08600;SR-01000272607;J-510516;SR-01000272607-1;Z56926658;3-(2-Hydroxyethyl)-2-sulfanylidene-2,3-dihydroquinazolin-4(1H)-one

Suppliers and Price of 3-(2-hydroxyethyl)-2-mercaptoquinazolin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(2-hydroxyethyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one
500mg
$ 310.00

American Custom Chemicals Corporation
3-(2-HYDROXYETHYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE 95.00%
5G
$ 1114.58

American Custom Chemicals Corporation
3-(2-HYDROXYETHYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE 95.00%
2.5G
$ 932.60

American Custom Chemicals Corporation
3-(2-HYDROXYETHYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE 95.00%
1G
$ 692.46

Total 5 raw suppliers

Chemical Property of 3-(2-hydroxyethyl)-2-mercaptoquinazolin-4(3H)-one

Chemical Property:

Vapor Pressure:1.93E-07mmHg at 25°C
Boiling Point:409.5°C at 760 mmHg
Flash Point:201.5°C
PSA：93.92000
Density:1.47g/cm³
LogP:0.67750
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:222.04629874
Heavy Atom Count:15
Complexity:283

Purity/Quality:

99% ^*data from raw suppliers

3-(2-hydroxyethyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C(=S)N2)CCO

Technology Process of 3-(2-hydroxyethyl)-2-mercaptoquinazolin-4(3H)-one

There total 5 articles about 3-(2-hydroxyethyl)-2-mercaptoquinazolin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 75-15-0,12122-00-8
carbon disulfide

: 118-48-9
isatoic anhydride

: 141-43-5
ethanolamine

: 16024-85-4
3-(2-hydroxy-ethyl)-2-thioxo-2,3-dihydro-1H-quinazolin-4-one

Guidance literature:: isatoic anhydride; ethanolamine; In N,N-dimethyl-formamide; at 40 ℃; Microwave irradiation;

carbon disulfide; In N,N-dimethyl-formamide; at 20 - 120 ℃; Microwave irradiation;
DOI:10.1002/jhet.2036

Reference yield: 75.0%

: 16024-82-1
methyl 2-isothiocyanatobenzoate

: 141-43-5
ethanolamine

: 16024-85-4
3-(2-hydroxy-ethyl)-2-thioxo-2,3-dihydro-1H-quinazolin-4-one

Guidance literature:: With triethylamine; In 1,4-dioxane; for 8h; Heating;
DOI:10.1080/10426500600867042

Reference yield:

: 134-20-3
2-carbomethoxyaniline

: 16024-85-4
3-(2-hydroxy-ethyl)-2-thioxo-2,3-dihydro-1H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / triethylamine / dioxane / 8 h / Heating

With triethylamine; In 1,4-dioxane;
DOI:10.1080/10426500600867042