2(3H)-FURANONE, 3-(p-BENZYLOXYBENZYLIDENE)DIHYDRO-

Base Information

• Chemical Name: 2(3H)-FURANONE, 3-(p-BENZYLOXYBENZYLIDENE)DIHYDRO-
• CAS No.: 73839-66-4
• Molecular Formula: C₁₈H₁₆O₃
• Molecular Weight: 280.323
• Mol file: 73839-66-4.mol

Synonyms:BRN 0024987;2(3H)-FURANONE, 3-(p-BENZYLOXYBENZYLIDENE)DIHYDRO-;73839-66-4;p-(Benzyloxy)-alpha-(2-hydroxyethyl)cinnamic acid gamma-lactone;4-18-00-00368 (Beilstein Handbook Reference)

Chemical Property of 2(3H)-FURANONE, 3-(p-BENZYLOXYBENZYLIDENE)DIHYDRO-

Chemical Property:

• Vapor Pressure: 1.68E-10mmHg at 25°C
• Boiling Point: 509.5°Cat760mmHg
• Flash Point: 220.9°C
• PSA: 35.53000
• Density: 1.225g/cm³
• LogP: 3.59590
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 280.109944368
• Heavy Atom Count: 21
• Complexity: 374

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COC(=O)C1=CC2=CC=C(C=C2)OCC3=CC=CC=C3
• Isomeric SMILES: C\1COC(=O)/C1=C\C2=CC=C(C=C2)OCC3=CC=CC=C3

Technology Process of 2(3H)-FURANONE, 3-(p-BENZYLOXYBENZYLIDENE)DIHYDRO-

There total 2 articles about 2(3H)-FURANONE, 3-(p-BENZYLOXYBENZYLIDENE)DIHYDRO- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-butanolide (96-48-0) + p-benzyloxybenzaldehyde (4397-53-9) → α-(4-Benzyloxybenzyliden)-butyrolacton (73839-66-4)

Guidance literature:

With sodium methylate; benzene;

DOI:10.1021/jo01083a009

Reference yield:

→ α-(4-Benzyloxybenzyliden)-butyrolacton (73839-66-4)

Guidance literature:

Butyrolacton, 4-Benzyloxybenzaldehyd, NaOMe, Benzol;

Reference yield:

α-(4-Benzyloxybenzyliden)-butyrolacton (73839-66-4) → α-(4-Acetoxybenzyliden)-butyrolacton (91903-44-5)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated aqueous hydrochloric acid; acetic acid

With hydrogenchloride; acetic acid;

DOI:10.1021/jo01083a009

upstream raw materials:

4-butanolide

p-benzyloxybenzaldehyde

Downstream raw materials:

3-((Ξ)-4-hydroxy-benzylidene)-dihydro-furan-2-one

3-(4-hydroxybenzyl)dihydrofuren-2(3H)-one

α-(4-Acetoxybenzyliden)-butyrolacton