3-[(4-Hydroxyphenyl)methyl]oxolan-2-one

Base Information

Chemical Name:3-[(4-Hydroxyphenyl)methyl]oxolan-2-one
CAS No.:91143-06-5
Molecular Formula:C₁₁H₁₂O₃
Molecular Weight:192.214
Hs Code.:
DSSTox Substance ID:DTXSID101227913

Synonyms:91143-06-5;DTXSID101227913;Dihydro-3-[(4-hydroxyphenyl)methyl]-2(3H)-furanone

Suppliers and Price of 3-[(4-Hydroxyphenyl)methyl]oxolan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-[(4-Hydroxyphenyl)methyl]oxolan-2-one

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:192.078644241
Heavy Atom Count:14
Complexity:207

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COC(=O)C1CC2=CC=C(C=C2)O

Technology Process of 3-[(4-Hydroxyphenyl)methyl]oxolan-2-one

There total 4 articles about 3-[(4-Hydroxyphenyl)methyl]oxolan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 547-65-9
α-methylene-γ-butyrolactone

: 4-hydroxybenzenediazonium tetrafluoroborate

: 91143-06-5
3-(4-hydroxybenzyl)dihydrofuren-2(3H)-one

Guidance literature:: α-methylene-γ-butyrolactone; 4-hydroxybenzenediazonium tetrafluoroborate; With sodium acetate; palladium diacetate; In methanol; at 20 ℃; Inert atmosphere;

With hydrogen; pyrographite; at 20 ℃; for 12h; under 750.075 Torr; Inert atmosphere;
DOI:10.1021/acs.joc.6b02207

Reference yield:

: 4736-30-5
3-((Ξ)-4-hydroxy-benzylidene)-dihydro-furan-2-one

: 91143-06-5
3-(4-hydroxybenzyl)dihydrofuren-2(3H)-one

Guidance literature:: With methanol; platinum; Hydrogenation;
DOI:10.1021/jo01083a009

Reference yield:

: 4397-53-9
p-benzyloxybenzaldehyde

: 91143-06-5
3-(4-hydroxybenzyl)dihydrofuren-2(3H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: sodium methylate; benzene

2: concentrated aqueous hydrochloric acid; acetic acid

3: platinum; methanol / Hydrogenation

With hydrogenchloride; methanol; sodium methylate; acetic acid; platinum; benzene;
DOI:10.1021/jo01083a009