7,8-Dioxabicyclo[4.2.2]decane

Base Information

• Chemical Name: 7,8-Dioxabicyclo[4.2.2]decane
• CAS No.: 52965-57-8
• Molecular Formula: C8H14O2
• Molecular Weight: 142.198
• DSSTox Substance ID: DTXSID10967438
• Mol file: 52965-57-8.mol

Synonyms:7,8-Dioxabicyclo[4.2.2]decane;7,8-Dioxabicyclo(4.2.2)decane;7,8-Dioxabicyclo(4,2,2)decane;52965-57-8;DTXSID10967438;GRPFSWFCSGHVIB-UHFFFAOYSA-N

Chemical Property of 7,8-Dioxabicyclo[4.2.2]decane

Chemical Property:

• Vapor Pressure: 1.98mmHg at 25°C
• Boiling Point: 170.1°Cat760mmHg
• Flash Point: 71.3°C
• Density: 1.011g/cm³
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 142.099379685
• Heavy Atom Count: 10
• Complexity: 99.8

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC2CCC(C1)OO2

Technology Process of 7,8-Dioxabicyclo[4.2.2]decane

There total 13 articles about 7,8-Dioxabicyclo[4.2.2]decane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

9,10-dioxabicyclo[4.2.2]dec-7-ene (52148-56-8) → 7,8-dioxa-bicyclo[4.2.2]decane (52965-57-8)

Guidance literature:

With diimide; In dichloromethane;

DOI:10.1016/0040-4039(92)88070-L

Reference yield: 88.0%

9,10-dioxabicyclo<4.2.2>deca-7-ene (52148-56-8) → 9,10-dioxabicyclo<4.2.2>decane (52965-57-8)

Guidance literature:

With potassium diazodicarboxylate; acetic acid; In dichloromethane; for 24h; Ambient temperature;

DOI:10.1016/S0040-4020(01)85713-6

Reference yield:

1,5-cis,cis-cyclooctadiene (1552-12-1,111-78-4) → 9-oxa-bicyclo[4.2.1]nonane (284-20-8) + 9-oxabicyclo[3.3.1]nonan-1-ol (37996-41-1) + 7,8-dioxa-bicyclo[4.2.2]decane (52965-57-8) + 9,10-dioxabicyclo<3.3.2>decane (65651-41-4)

Guidance literature:

With sodium hydroxide; sodium tetrahydroborate; potassium chloride; mercury(II) diacetate; dihydrogen peroxide; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1039/P19810000621

upstream raw materials:

1,5-cis,cis-cyclooctadiene

9,10-dioxabicyclo[4.2.2]dec-7-ene

7,8-dioxabicyclo<4.2.2>deca-2,4,9-triene

1,3-cyclooctadiene

Downstream raw materials:

4-tosyloxycyclooctanone

hexanedial

cyclooctane-1,4-dione