Z-Met-OH

Base Information Edit

Chemical Name:Z-Met-OH
CAS No.:1152-62-1
Molecular Formula:C13H17NO4S
Molecular Weight:283.348
Hs Code.:29242990
European Community (EC) Number:214-570-5
DSSTox Substance ID:DTXSID901306173
Nikkaji Number:J80.206I
Wikidata:Q106902933
ChEMBL ID:CHEMBL1713556
Mol file:1152-62-1.mol

Synonyms:1152-62-1;Z-Met-OH;N-CBZ-L-METHIONINE;Z-L-Methionine;Cbz-L-Methionine;CBZ-MET-OH;C13H17NO4S;(2S)-4-methylsulfanyl-2-(phenylmethoxycarbonylamino)butanoic acid;MFCD00065124;N-[(benzyloxy)carbonyl]-L-methionine;L-Methionine, N-[(phenylmethoxy)carbonyl]-;N-Carbobenzoxy-L-methionine;N-Carbobenzyloxy-L-methionine;N-(Benzyloxycarbonyl)-L-methionine;EINECS 214-570-5;N-Cbz methionine;BENZYLOXYCARBONYL-L-METHIONINE;(S)-Cbz methionine;N-[(Benzyloxy)carbonyl](methyl)homocysteine #;Z-L-Methionine, 97%;Z-L-MET-OH;MLS000521452;N-Benzyloxycarbonyl methionine;SCHEMBL1157282;CHEMBL1713556;DTXSID901306173;HMS2453O15;((Benzyloxy)carbonyl)-L-methionine;(2S)-2-{[(benzyloxy)carbonyl]amino}-4-(methylsulfanyl)butanoic acid;BBL012095;STK730616;AKOS001661703;AKOS015923286;AM81984;CCG-114114;CS-W014002;HY-W013286;N-BENZYLOXYCARBONYL-L-METHIONINE;N-ALPHA-CARBOBENZOXY-L-METHIONINE;NCGC00245950-01;AS-35009;N-[(Phenylmethoxy)carbonyl]-L-methionine;SMR000131860;Z-Met-OH, puriss., >=99.0% (T);N-ALPHA-BENZYLOXYCARBONYL-L-METHIONINE;N-{[(Phenylmethyl)oxy]carbonyl}-L-methionine;EN300-5014673;A803399;SR-01000084222;J-300199;Q-101650;SR-01000084222-1;(S)-2-(benzyloxycarbonylamino)-4-(methylthio)butanoic acid;(S)-2-(((BENZYLOXY)CARBONYL)AMINO)-4-(METHYLTHIO)BUTANOIC ACID;(2S)-2-(benzyloxycarbonylamino)-4-methylsulfanyl-butanoic acid;N-Cbz-L-Methionine

Suppliers and Price of Z-Met-OH

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Cbz-L-methionine
50g
$ 265.00

TCI Chemical
N-Carbobenzoxy-L-methionine >98.0%(T)
25g
$ 109.00

TCI Chemical
N-Carbobenzoxy-L-methionine >98.0%(T)
5g
$ 33.00

SynQuest Laboratories
N-Cbz-L-Methionine
100 g
$ 276.00

Sigma-Aldrich
Z-L-Methionine 97%
5g
$ 45.00

Iris Biotech GmbH
Z-L-Met-OH
100 g
$ 202.50

Iris Biotech GmbH
Z-L-Met-OH
25 g
$ 81.00

Frontier Specialty Chemicals
Z-L-Methionine 98%
5g
$ 29.00

Crysdot
Z-Met-OH 98%
500g
$ 228.00

Crysdot
Z-Met-OH 98%
100g
$ 57.00

Total 87 raw suppliers

Chemical Property of Z-Met-OH Edit

Chemical Property:

Appearance/Colour:White to off-white powder
Vapor Pressure:5.22E-11mmHg at 25°C
Melting Point:66-70 ºC
Refractive Index:-26 ° (C=1, MeOH)
Boiling Point:504.7 °C at 760mmHg
PKA:3.81±0.10(Predicted)
Flash Point:259 °C
PSA：100.93000
Density:1.253 g/cm³
LogP:2.51000
Storage Temp.:2-8°C
Solubility.:almost transparency in Methanol
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:283.08782920
Heavy Atom Count:19
Complexity:292

Purity/Quality:

99% ^*data from raw suppliers

N-Cbz-L-methionine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 22-24/25-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CSCCC(C(=O)O)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES:CSCC[C@@H](C(=O)O)NC(=O)OCC1=CC=CC=C1
Uses N-Cbz-L-methionine is a protected form of L-Methionine (M260440). L-Methionine is an essential amino acid that is obtained from our diet. L-Methionine can be found in grain legumes (such as lentils), and poultry. L-Methionine’s main function is to act as the primary “Start” sequence on mRNA so that the ribosomes can start translating the mRNA into proteins.

Technology Process of Z-Met-OH

There total 29 articles about Z-Met-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 63-68-3,26062-47-5,58576-49-1
L-methionine

: 501-53-1,94274-21-2
benzyl chloroformate

: 1152-62-1
Cbz-Met-OH

Guidance literature:: fipronilβ-cyclodextrin; In various solvent(s); at 20 ℃; for 0.15h; pH=8;
DOI:10.1016/j.tetlet.2006.06.162

Reference yield: 95.0%

: 16874-01-4
benzyl (S)-1-(tert-butoxycarbonyl)-3-(methylthio)propylcarbamate

: 1152-62-1
Cbz-Met-OH

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; for 0.416667h; Ambient temperature;
DOI:10.1016/S0040-4039(00)79116-7