n-Cyclohexylhydrazinecarboxamide

Base Information

• Chemical Name: n-Cyclohexylhydrazinecarboxamide
• CAS No.: 52662-76-7
• Molecular Formula: C7H15N3O
• Molecular Weight: 157.216
• Hs Code.: 2928000090
• European Community (EC) Number: 872-040-4
• NSC Number: 94941
• DSSTox Substance ID: DTXSID80294167
• Nikkaji Number: J1.570.635J
• Wikidata: Q82033291
• Mol file: 52662-76-7.mol

Synonyms:n-cyclohexylhydrazinecarboxamide;52662-76-7;1-amino-3-cyclohexylurea;3-amino-1-cyclohexylurea;N-cyclohexylhydrazinecarboxamide hydrochloride;NSC94941;4-cyclohexylsemicarbazide;NCIOpen2_001316;Oprea1_504789;SCHEMBL3077959;DTXSID80294167;VZVGVHNZWUQMRZ-UHFFFAOYSA-N;NSC-94941;AKOS000116156;CS-0307623;FT-0693723;EN300-03728;Z56838483

Chemical Property of n-Cyclohexylhydrazinecarboxamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 67.15000
• Density: 1.09g/cm³
• LogP: 1.97410
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 157.121512110
• Heavy Atom Count: 11
• Complexity: 132

Purity/Quality:

99% ^*data from raw suppliers

N-cyclohexylhydrazinecarboxamidehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)NC(=O)NN

Technology Process of n-Cyclohexylhydrazinecarboxamide

There total 10 articles about n-Cyclohexylhydrazinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

Cyclohexyl isocyanate (3173-53-3) → (N-cyclohexylhydrazinecarboxamide) (52662-76-7)

Guidance literature:

With hydrazine hydrate; In dichloromethane; at -60 - 20 ℃;

DOI:10.1021/jm021074j

Reference yield:

cyclohexylcarbamic acid phenyl ester (56379-88-5) → (N-cyclohexylhydrazinecarboxamide) (52662-76-7)

Guidance literature:

With hydrazine hydrate; In 1,2-dimethoxyethane; at 80 ℃; for 12h;

DOI:10.1021/acs.orglett.7b02312

Reference yield:

cyclohexylamine (108-91-8,157973-60-9) → (N-cyclohexylhydrazinecarboxamide) (52662-76-7)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine

2: hydrazine hydrate / 1,4-dioxane / 18 h / 20 °C

With hydrazine hydrate; triethylamine; In 1,4-dioxane;

DOI:10.3109/14756366.2012.663366

upstream raw materials:

N-Cyclohexyl-carbamidsaeure-(2-hydroxyphenyl)-ester

Cyclohexyl isocyanate

cyclohexylamine

N-cyclohexyl-1H-benzo[d][1,2,3]triazole-1-carboxamide

Downstream raw materials:

4-Cyclohexyl-1-benzyliden-semicarbazid

2-Amino-5-cyclohexylamino-1,3,4-oxadiazol

2,5-Dicyclohexylamino-1,3,4-oxadiazol

N-cyclohexyl-3,5-dimethyl-1H-pyrazole-1-carboxamide