phenyl N-cyclohexylcarbamate

Base Information

• Chemical Name: phenyl N-cyclohexylcarbamate
• CAS No.: 56379-88-5
• Molecular Formula: C13H17 N O2
• Molecular Weight: 219.283
• European Community (EC) Number: 661-807-7
• NSC Number: 128823
• DSSTox Substance ID: DTXSID30971810
• Nikkaji Number: J604.323B
• Wikidata: Q82955419
• ChEMBL ID: CHEMBL77271
• Mol file: 56379-88-5.mol

Synonyms:phenyl N-cyclohexylcarbamate;56379-88-5;CHEMBL77271;phenyl cyclohexylcarbamate;Cyclohexyl-carbamic acid phenyl ester;NSC128823;Maybridge3_000520;MLS000851154;SCHEMBL1532563;DTXSID30971810;HMS1432H14;HMS2800J16;BDBM50128575;AKOS008928527;Phenyl hydrogen cyclohexylcarbonimidate;CCG-233156;NSC-128823;IDI1_011907;SMR000457397;BRD-K43679200-001-07-8

Chemical Property of phenyl N-cyclohexylcarbamate

Chemical Property:

• Vapor Pressure: 0.000329mmHg at 25°C
• Boiling Point: 319.9°C at 760 mmHg
• Flash Point: 147.3°C
• Density: 1.1g/cm³
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 219.125928785
• Heavy Atom Count: 16
• Complexity: 218

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC(CC1)NC(=O)OC2=CC=CC=C2

Technology Process of phenyl N-cyclohexylcarbamate

There total 12 articles about phenyl N-cyclohexylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

cyclohexanylcarbonyl chloride (2719-27-9) + phenol (108-95-2,27073-41-2) → cyclohexylcarbamic acid phenyl ester (56379-88-5)

Guidance literature:

cyclohexanylcarbonyl chloride; With sodium azide; N-benzyl-N,N,N-triethylammonium chloride; In toluene; at 60 - 80 ℃; for 1.25h;

phenol; In toluene; at 20 ℃;

DOI:10.1080/00304940409355385

Reference yield: 97.0%

cyclohexylamine (108-91-8,157973-60-9) + phenyl chloroformate (1885-14-9) → cyclohexylcarbamic acid phenyl ester (56379-88-5)

Guidance literature:

at 20 ℃; Reagent/catalyst; Temperature;

DOI:10.1002/chem.202103196

Reference yield: 97.0%

phenyl Salicylate (118-55-8) + Cyclohexyl isocyanate (3173-53-3) → 3-cyclohexyl-benzo[e][1,3]oxazine-2,4-dione (3417-55-8) + cyclohexylcarbamic acid phenyl ester (56379-88-5)

Guidance literature:

With dmap; triethylamine; In N,N-dimethyl-formamide; for 72h; Ambient temperature;

DOI:10.1016/S0040-4039(98)00223-8

upstream raw materials:

cyclohexylamine

1-Phenoxycarbonyl-benzotriazol

chloromethyl phenyl carbonate

dichloromethyl phenyl carbonate

Downstream raw materials:

C₁₅H₁₆N₂O₄

(N-cyclohexylhydrazinecarboxamide)

5-benzyl-3-cyclohexylimidazolidine-2,4-dione

Glibenclamid